Monoprost (Latanoprost)

Name: Monoprost
Brand: Laboratoires Thea
SKU: 7551
Availability: InStock

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Qty-Price (USD)

Type:

Product: Monoprost 30 x 0.2ml Droperette

Manufacturer: Laboratoires Thea

Country: Canada

Dosage: 50 mcg/ml

Qty-Price (USD):

Generic Equivalent of Monoprost

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Qty-Price (USD)

There is no generic product of Monoprost.

Monoprost Information

medically reviewed by Dr. HaVy Ngo, Pharmacist on June 13, 2025.

Monoprost at CanadaPharmacyOnline.com

Brand Monoprost, manufactured by Labtician Thea Ophthalmics Inc., is available in Canada.

The generic version of preservative-free latanoprost is currently unavailable (at this pharmacy).

Dosage:

Monoprost is an ophthalmic solution (eye drop) available as a concentration of 50 mcg/ml, packaged as 30 single-use 0.2 ml drops.

Your doctor will determine the appropriate dose based on your individual needs and medical condition.

Usage:

Brand Monoprost (Latanoprost) is a prescription medication used to treat conditions like open-angle glaucoma and ocular hypertension. It is the first preservative-free prostaglandin in Canada. It’s specifically formulated without preservatives like benzalkonium chloride (BAK), which can irritate some patients' eyes.

For more information, refer to the official website of Monoprost: https://www.monoprost.ca/en.

Mechanism of Action:
Monoprost (latanoprost) belongs to a class of medications called prostaglandin F2α analogues. Its primary function is treating glaucoma and ocular hypertension; it involves significantly reducing intraocular pressure (IOP) by increasing the outflow of aqueous humor from the eye. It converts the active ingredient, latanoprost, into latanoprost acid within the eye, binding to specific receptors in the ciliary muscle and sclera. Latanoprost acid helps to remodel these tissues, making it easier for the fluid to drain out of the eye. This improved outflow of aqueous humor effectively reduces the pressure within the eye, essential for managing conditions like open-angle glaucoma and ocular hypertension.

Use Monoprost exactly as your doctor prescribes. Do not change your dosage or stop using the medication without consulting your doctor. Follow the instructions in the product monograph in Canada: https://pdf.hres.ca/dpd_pm/00035751.PDF.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Monoprost, it is essential to discuss all possible aspects with your doctor or pharmacist.

Side Effects:

The information below is a partial list of side effects; individual reactions can vary. Before starting Monoprost, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common side effects: These are examples of some common side effects of Monoprost, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Blurred vision.
• Changes to eyelashes: These can become longer, thicker, darker, and more numerous. This effect is often reversible upon stopping the medication.
• Darkening of the skin around the eyelids.
• Dry eyes.
• Eye irritation: Burning, stinging, grittiness, itching, or a sensation of a foreign body in the eye.
• Eye pain.
• Eyelid inflammation (blepharitis).
• Gradual change in eye color: This is a well-known side effect, where the iris (colored part of the eye) may gradually become more brown. This change is more likely in individuals with mixed-color eyes (e.g., blue-brown, grey-brown) and can be permanent, even after discontinuing the drops.
• Redness of the eye (conjunctival hyperemia).
• Sensitivity to light (photophobia).

Serious or rare side effects: Stop taking Monoprost and seek immediate medical attention if you experience any of the following:
• Herpetic keratitis (eye infection caused by the herpes simplex virus).
• Inflammation inside the eye (uveitis or iritis).
• Inflammation of the cornea (keratitis).
• Macular edema (swelling in the central part of the retina), particularly in patients with certain risk factors like aphakia or a torn posterior lens capsule.
• Swelling of the eyelids (eyelid edema).

Systemic side effects (generally less common): The following are concerning and should be discussed with your doctor; they typically do not require immediate medical attention.
• Asthma or worsening of asthma symptoms (e.g., wheezing, shortness of breath).
• Chest pain or angina.
• Dizziness.
• Headache.
• Muscle and joint pain (myalgia, arthralgia).
• Nausea and vomiting.
• Palpitations (fast heart rate).
• Skin rash.

Contraindications:

This is not an exhaustive list of contraindications. It is crucial to discuss all your medical conditions, past, and present, and all medications you are taking with your doctor or pharmacist before starting Monoprost.

Monoprost should not be used if:
• Concomitant use of other prostaglandin analogues: Using two or more analogues or derivatives simultaneously is not recommended as it can paradoxically elevate intraocular pressure.
• Hypersensitivity/Allergy: Individuals with a known allergy to latanoprost or any other Monoprost ingredients should not use it.

Tell your doctor about all your medical conditions, past and present, before starting Monoprost. This is crucial because certain conditions can also lead to further contraindications. These conditions may include, but are not limited to:
• Active Herpes Simplex Keratitis: Patients with an active eye infection caused by the herpes simplex virus (HSV) should avoid Monoprost. Caution is also advised for those with a history of recurrent herpetic keratitis, specifically associated with prostaglandin analogues.
• Active Intraocular Inflammation: Monoprost is generally not recommended for patients with active inflammation inside the eye, such as iritis or uveitis, as it may worsen these conditions.
• Aphakic or pseudophakic patients with torn posterior lens capsules: These patients are at increased risk of macular edema.
• Patients with a history of intraocular inflammation (iritis/uveitis).
• Patients with known risk factors for cystoid macular edema: This includes conditions like diabetic retinopathy and retinal vein occlusion.
• Patients with liver or kidney impairment: Latanoprost has not been extensively studied in these populations.
• Patients with severe or uncontrolled asthma.

Drug Interactions:

Before taking Monoprost, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the official Monoprost website: https://www.monoprost.ca/en.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Monoprost may interact with other medicines such as:
• Other Ophthalmic Medications: In general, if you are using other eye drops, it's a good practice to wait at least 5 minutes between the application of each medication to ensure proper absorption and to prevent potential interactions.
• Other Prostaglandin Analogues: Concomitant use of Monoprost with other prostaglandin analogues (e.g., bimatoprost, travoprost, tafluprost) or their derivatives should generally be avoided. Using multiple prostaglandin analogue can paradoxically increase intraocular pressure, counteracting the intended therapeutic effect.
• Thiomersal-containing Eye Drops: If you use other eye drops that contain thiomersal (a preservative), a precipitate may form when mixed with Monoprost. To avoid this, it's recommended to administer eye drops at least 5 minutes apart.

Pregnancy and Breastfeeding:

Monoprost is generally not recommended during pregnancy or breastfeeding. For pregnant individuals, the safety of latanoprost hasn't been definitively established in humans, and there are theoretical concerns that prostaglandins could affect the course of pregnancy or the unborn baby. For breastfeeding mothers, latanoprost and its metabolites may pass into breast milk, potentially posing a risk to the infant. Discuss the potential risks and benefits with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Use in Children:

Monoprost is not approved for use in children under the age of 18 due to limited clinical trials in that age group. The active ingredient, latanoprost, is sometimes used “off-label” by paediatric ophthalmologists for specific cases of pediatric glaucoma or ocular hypertension. This off-label use occurs when the potential benefits of lowering intraocular pressure outweigh the risks, particularly in conditions like juvenile open-angle glaucoma, where other treatments might be less effective. Although research is ongoing, existing data suggest a generally acceptable safety profile in children, with side effects similar to those in adults. Always consult your child’s doctor for the most appropriate and safest treatment.

Frequently Asked Questions about Monoprost at CanadaPharmacyOnline.com

Why is Monoprost more affordable in Canada than in the United States?

Prescription drug prices, including Monoprost, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs than the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a generic for Monoprost?

Yes, there is a generic alternative for this product, called Latanoprost.

Can I buy over the counter from you?

No, Monoprost requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

What should I avoid while taking Monoprost?

When you use Monoprost, you might have blurred vision for a short time. If this happens to you, do not drive or use any tools or machines until your vision becomes clear again.

Can I wear contact lenses while using Monoprost?

If you wear contact lenses, you should remove them before using Monoprost and wait for at least 15 minutes before putting them back in.

How long does Monoprost take to start working?

The reduction of intraocular pressure starts approximately 2 to 4 hours after the first administration.

How should I store Monoprost?

Unopened bottles should be stored in the refrigerator. Do not freeze. Store opened bottles at room temperature in a dry place. Keep out of sight and reach of children.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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