Ondissolve (Ondansetron)

Name: Ondissolve
Brand: Takeda
SKU: 6949
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Ondissolve Orally Disintegrating Film

Manufacturer: Takeda

Country: Canada

Dosage: 4 mg

Qty-Price (USD):

Type:

Product: Ondissolve Orally Disintegrating Film

Manufacturer: Takeda

Country: Canada

Dosage: 8 mg

Qty-Price (USD):

Generic Equivalent of Ondissolve

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

There is no generic product of Ondissolve.

Ondissolve Information

Ondissolve at CanadaPharmacyOnline.com

The manufacturer of brand-name Ondissolve is Takeda. It is available in many countries worldwide, including Canada.

The generic ondansetron is currently unavailable (at this pharmacy).

Dosage:

Ondissolve (ondansetron) is available in the following strengths at this pharmacy:
• Film: 4 mg and 8 mg orally disintegrating film (ODF).

The dose depends on the condition being treated and tolerability.

Usage:

Ondissolve (ondansetron) is a selective serotonin 5-HT3 receptor antagonist indicated for the prevention and treatment of nausea and vomiting induced by cytotoxic chemotherapy and radiotherapy, and for the prevention and treatment of post-operative nausea and vomiting (PONV). The orally disintegrating film (ODF) formulation is particularly convenient for patients who are already nauseated and have difficulty swallowing conventional tablets, as it dissolves quickly on the tongue without water.

Mechanism of Action Ondansetron works by acting as a highly specific shield against the body's natural vomiting chemical, serotonin. Medical treatments like chemotherapy, radiation, or surgery can cause cells in your stomach to release a massive wave of serotonin. When this serotonin attaches to 5-HT3 receptors in your gut and your brain's vomiting center, it sets off the sickness reflex. Ondissolve films dissolve instantly to release the drug, which parks directly inside these receptors. By safely blocking the serotonin from attaching, it cuts off the signal before it can trigger nausea and vomiting.

Use Ondissolve exactly as your doctor prescribes, as directed in the product monograph. Ensure your mouth is empty. Using a dry finger, remove one thin film strip from its pouch and place it directly on top of your tongue. It will dissolve rapidly in saliva within seconds and can be swallowed without water. Do not chew or swallow the film whole.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Ondissolve, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Ondissolve (ondansetron). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Ondissolve; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning.
• Constipation
• Diarrhea
• Fatigue or weakness
• Headache (the most commonly reported side effect)
• Warmth or tingling sensation

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• QT Interval Prolongation and Cardiac Arrhythmias: Palpitations, fainting, or an irregular heartbeat.
• Serotonin Syndrome: Agitation, confusion, rapid heart rate, fever, sweating, shivering, muscle twitching, or diarrhea.
• Severe Allergic Reaction (Anaphylaxis): Hives, swelling of the face, lips, tongue, or throat, drop in blood pressure, or difficulty breathing.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Ondissolve, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Ondissolve/ondansetron if:
• Allergies: Known hypersensitivity to ondansetron, other 5-HT3 antagonists, or any ingredient.
• Apomorphine: Ondansetron is contraindicated with apomorphine due to the risk of severe hypotension and loss of consciousness.
• Pre-existing significant QT prolongation.

Tell your doctor about all of your medical conditions, past and present, before starting Ondissolve. This is crucial as certain conditions affect the drug's safety.
• Electrolyte abnormalities
• Heart conditions
• Liver disease

Drug Interactions:

Before taking Ondissolve, discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the product monograph at https://pdf.hres.ca/dpd_pm/00035147.PDF.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Ondissolve. Ondissolve may interact with other medicines, including but not limited to:
• Apomorphine: Contraindicated
• Drugs that prolong the QT interval (e.g., certain antiarrhythmics, antipsychotics, antibiotics, methadone): Increased risk of serious cardiac arrhythmias.
• Phenytoin, carbamazepine, rifampicin (CYP3A4 inducers): May reduce ondansetron blood levels.
• Serotonergic drugs (SSRIs, SNRIs, MAOIs, triptans, tramadol, fentanyl): Increased risk of serotonin syndrome.

Pregnancy and Breastfeeding:

Ondansetron is commonly used to manage nausea and vomiting in pregnancy, including severe morning sickness (hyperemesis gravidarum), under medical supervision. Some studies have raised questions about cardiovascular risks to the fetus with first-trimester use; discuss the risks and benefits carefully with your doctor. Ondansetron passes into breast milk; discuss with your doctor before breastfeeding.

Use in Children:

Ondissolve ODF is approved for use in children aged 4 years and older to treat CINV. The dose in children is based on body weight. Consult your doctor for appropriate dosing.

Frequently Asked Questions about Ondissolve at Canada Pharmacy Online

Why is Ondissolve more affordable in Canada than in the United States?

Prescription drug prices, including Ondissolve, are generally lower in Canada than in the U.S. due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1.866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Ondissolve I can order at once?

CanadaPharmacyOnline.com can dispense up to a 3-month supply of Ondissolve per your doctor's prescription.

Can I buy Ondissolve from you over the counter?

No, Ondissolve requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Ondissolve?

No, the generic equivalent is currently unavailable (at this pharmacy).

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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