Prometrium (Progesterone)

Name: Prometrium
Brand: Brand
SKU: 1910
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Prometrium Capsule

Manufacturer: Brand

Country: New Zealand

Dosage: 100 mg

Qty-Price (USD):

Type:

Product: Prometrium Capsule

Manufacturer: Organon

Country: Canada

Dosage: 100 mg

Qty-Price (USD):

Generic Equivalent of Prometrium

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Progesterone Capsule

Manufacturer: Generic

Country: India

Dosage: 100 mg

Qty-Price (USD):

Type:

Product: Progesterone Gel Capsule

Manufacturer: Generic

Country: Canada

Dosage: 100 mg

Qty-Price (USD):

Type:

Product: Progesterone Capsule

Manufacturer: Generic

Country: India

Dosage: 200 mg

Qty-Price (USD):

Type:

Product: Progesterone Capsule Soft Gel

Manufacturer: Generic

Country: Turkey

Dosage: 200 mg

Qty-Price (USD):

Type:

Product: Progesterone (Susten - Sun Pharma)

Manufacturer: Generic

Country: India

Dosage: 400 mg

Qty-Price (USD):

Prometrium Information

medically reviewed by Dr. HaVy Ngo, Pharmacist on May 29, 2025.

Prometrium and Progesterone at CanadaPharmacyOnline.com

Brand Prometrium (progesterone) is manufactured by Organon in Canada. It is also manufactured by Organon in New Zealand, under the brand name Utrogestan.

Generic progesterone is sourced from manufacturers that meet applicable regulatory standards for safety, efficacy, and quality. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Progesterone:

Generic progesterone contains the same active ingredient as brand-name Prometrium and is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as Prometrium. Studies have demonstrated bioequivalence between generic and brand-name progesterone, meaning they have comparable absorption rates and overall effects. However, individual responses to any medication can vary. Talk to your doctor or pharmacist if you have any questions about using generic progesterone.

For more information about generic drug approval and bioequivalence, you can visit the FDA website: https://www.fda.gov/drugs/buying-using-medicine-safely/generic-drugs

Dosage:

At this pharmacy, brand Prometrium is available in 100 mg capsules, and generic progesterone is available in 100 mg, 200 mg, and 400 mg capsules. Progesterone is also available in other forms, such as gel and soft gel capsules.

Your doctor will determine the appropriate dose based on your needs and medical conditions.

Usage:

Prometrium (progesterone) is a prescription medication used in women for several reasons. These include helping to regulate menstrual periods, treating secondary amenorrhea (absence of menstrual periods in a woman who has previously had them), and as part of hormone replacement therapy (HRT) in women who have gone through menopause and are also taking estrogen. In HRT, progesterone helps to protect the uterus from changes that can lead to cancer of the uterine lining (endometrial hyperplasia) caused by estrogen alone. Your doctor determines the dosage of progesterone, which will depend on the condition being treated and your individual needs. It is crucial to follow your doctor's prescribed dosing regimen. (source: product labeling information, https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/019781s013lbl.pdf)

Mechanism of Action:
Prometrium (progesterone) is a natural female hormone. It works by acting on the uterus (womb). In women who are not pregnant, progesterone is produced by the ovaries during the second half of the menstrual cycle. It helps to prepare the lining of the uterus for a possible pregnancy. If pregnancy does not occur, progesterone levels drop, leading to menstruation. In hormone replacement therapy, progesterone helps to balance the effects of estrogen on the uterus.

Take Prometrium exactly as your doctor prescribes, following the instructions in the official consumer information: https://www.organon.com/canada-en/wp-content/uploads/sites/5/2021/05/PROMETRIUM-CI_E.pdf. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Prometrium, it is essential to discuss all possible aspects with your doctor or pharmacist.

Side Effects:

The information below is a partial list of side effects; individual reactions can vary. Before starting Prometrium, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common side effects: These are examples of some common side effects of Prometrium, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Abdominal pain
• Breast tenderness
• Constipation
• Dizziness
• Fatigue
• Headache
• Insomnia
• Mood changes (including irritability, anxiety, nervousness)
• Nausea, vomiting

Serious or rare side effects: Stop taking Prometrium and seek immediate medical attention if you experience any of the following:
• Changes in vision, including sudden partial or complete loss of vision
• Depression
• Increase in blood pressure.
• Jaundice (yellowing of the skin or eyes)
• Severe headache
• Severe nausea or vomiting
• Signs of blood clots or other thromboembolic disorders (e.g., pain, swelling, warmth in the leg, sudden chest pain, shortness of breath)
• Signs of heart problems or heart attack (e.g., chest pain, shortness of breath, increased sweating, nausea or vomiting, light-headedness, rapid or irregular heartbeat)
• Stroke symptoms (e.g., sudden numbness or weakness, confusion, trouble speaking or understanding)

Contraindications:

This is not an exhaustive list of contraindications. It is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist before starting Prometrium.

Prometrium should not be used if:
• You are allergic to progesterone or any of the ingredients in Prometrium.
• You have had active or recent blood clots in the legs, lungs, or eyes.
• You have had an active or recent heart attack or stroke.
• You have liver disease.
• You have known or suspected breast cancer or other hormone-sensitive cancers.
• You have known or suspected estrogen-dependent neoplasia.
• You have undiagnosed abnormal vaginal bleeding.
• You have had a known or missed abortion.

Tell your doctor about all of your medical conditions, past and present, before starting Prometrium. This is crucial because certain conditions can affect whether Prometrium is right for you. These conditions may include, but are not limited to:
• Asthma
• Depression
• Diabetes
• Epilepsy
• Fluid retention (edema)
• Heart problems
• History of smoking
• History of thromboembolic disorders (such as blood clots, deep vein thrombosis, pulmonary embolism, retinal thrombosis)
• Kidney problems
• Migraine headaches
• Visual abnormalities

Dizziness and Drowsiness:
Prometrium may cause dizziness or drowsiness. Do not drive, operate machinery, or engage in activities that require alertness until you understand how it affects you.

Drug Interactions:

Before taking Prometrium, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the product monograph in Canada, https://pdf.hres.ca/dpd_pm/00060583.PDF.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Prometrium may interact with other medicines, including but not limited to certain seizure medications (e.g., phenobarbital, phenytoin, carbamazepine), rifampin, certain antibiotics or antifungal medications (e.g., erythromycin, ketoconazole, itraconazole), and St. John's Wort.

Pregnancy and Breastfeeding:

Prometrium may be used during pregnancy for certain conditions under the guidance of a healthcare professional. Progesterone is present in breast milk. Breastfeeding women should discuss the risks and benefits with their doctor before using Prometrium.

Use in Children:

The safety and effectiveness of Prometrium have not been established in children. Talk to your doctor or pharmacist before using this medication in children.

Frequently Asked Questions about Prometrium at CanadaPharmacyOnline.com:

Why is Prometrium more affordable in Canada than in the United States?

Prescription drug prices, including Prometrium, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

Can the Prometrium capsule be split or crushed?

Follow your doctor or pharmacist's instructions. The capsules are generally meant to be swallowed whole. Do not open, crush, or chew the capsules unless specifically instructed by your healthcare provider.

Can I take Prometrium with food?

Follow your doctor’s instructions. Depending on your individual needs and how your body reacts to the medication, they may recommend taking it with or without food. Taking it with food might help if you experience stomach upset.

What should I do if I miss a dose?

Take the missed dose as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How long does it take for Prometrium to work?

The time it takes for Prometrium to work can vary depending on the condition being treated. Follow your doctor’s instructions carefully, and do not stop taking the medication until you have completed the entire prescribed course of treatment.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many capsules I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of three months' supply of Prometrium at once, per your doctor's prescription.

Can I buy over the counter from you?

No, Prometrium requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Blog Post:

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News:

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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