Resolor (Prucalopride Succinate)

Name: Resolor
Brand: Janssen-Cilag
SKU: 6820
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Resolor (Resotrans)

Manufacturer: Janssen-Cilag

Country: Australia

Dosage: 1 mg

Qty-Price (USD):

Type:

Product: Resolor (Resotran)

Manufacturer: Amdipharm

Country: Canada

Dosage: 1 mg

Qty-Price (USD):

Type:

Product: Resolor (Resotrans)

Manufacturer: Janssen-Cilag

Country: New Zealand

Dosage: 2 mg

Qty-Price (USD):

Type:

Product: Resolor (Resotran)

Manufacturer: Amdipharm

Country: Canada

Dosage: 2 mg

Qty-Price (USD):

Generic Equivalent of Resolor

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Prucalopride Succinate

Manufacturer: Generic

Country: Canada

Dosage: 1 mg

Qty-Price (USD):

Type:

Product: Prucalopride Succinate

Manufacturer: Generic

Country: India

Dosage: 1 mg

Qty-Price (USD):

Type:

Product: Prucalopride Succinate

Manufacturer: Generic

Country: Canada

Dosage: 2 mg

Qty-Price (USD):

Type:

Product: Prucalopride Succinate

Manufacturer: Generic

Country: India

Dosage: 2 mg

Qty-Price (USD):

Resolor Information

medically reviewed by Carol Hou (BSc. Pharm) on April 28, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Resolor and Prucalopride Succinate at CanadaPharmacyOnline.com

Prucalopride succinate is marketed under various brand names, including Resolor, Motegrity, and Resotran, and the distribution rights vary by country. Brand Resolor marketed as Resotran (prucalopride Succinate) manufactured by Janssen-Cilag is available in many countries including Australia, and New Zealand. The brand from Canada is manufactured by Janssen Inc, and distributed by Amdipharm. In the United States, prucalopride is marketed as Motegrity by Takeda Pharmaceuticals. Pharmaceutical distribution and marketing rights are subject to change; verify information with official regulatory sources.

Generic prucalopride succinate is sourced from manufacturers meeting applicable local regulatory standards for safety, efficacy, and quality. The specific manufacturer of dispensed medication may vary.

Important Information about Generic Prucalopride Succinate:

Generic prucalopride succinate contains the same active ingredient as brand-name Resolor and is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as Resolor. Studies have demonstrated bioequivalence between generic and brand-name prucalopride succinate, meaning they have comparable absorption rates and overall effects. However, individual responses to any medication can vary. Talk to your doctor or pharmacist, if you have any questions about using generic prucalopride succinate.

For more information about generic drug approval and bioequivalence, you can visit the FDA website: https://www.fda.gov/drugs/buying-using-medicine-safely/generic-drugs

Dosage:

Brand Resolor and generic prucalopride succinate are available in 1 and 2 mg oral tablets.

Your doctor will determine the appropriate dose based on your needs and medical conditions.

Usage:

Resolor (prucalopride succinate) is a prescription medication used for the treatment of chronic constipation in adults for whom laxatives do not work well enough. (source: product labeling information)

Mechanism of Action
Prucalopride Succinate is in a class of medications called serotonin receptor agonists, specifically a highly selective 5-HT4 receptor agonist. It works by stimulating 5-HT4 receptors in the gastrointestinal tract, enhancing colonic motility and increasing the rhythmic contractions of the colon muscles. These contractions help to move stool through the colon, thereby relieving constipation.

Take Resolor orally exactly as your doctor prescribes, following the instructions in the patient information leaflet accompanying the medication. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Resolor, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects

The information below outlines potential side effects associated with Resolor. It is not an exhaustive list, and individual reactions can vary. Before starting Resolor, it is crucial to discuss possible side effects and risks with your doctor or pharmacist.

Common side effects - These are some common side effects of Resolor, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning or if you experience any other concerning symptoms.
• Abdominal pain;
• Abnormal bowel sounds;
• Decreased appetite;
• Diarrhea (if you experience severe or persistent diarrhea, contact your doctor immediately);
• Dizziness;
• Dyspepsial;
• Fatigue;
• Flatulence;
• Headache;
• Nausea;
• Vomiting

Serious or rare side effects- Stop taking Resolor and seek immediate medical attention or call emergency services if you experience any of the following:
• Allergic reaction including angioedema, hives, and shortness of breath
• Heart rhythm issues (palpitations, irregular heartbeat, and rarely, atrial fibrillation)
• Rare mental health changes (mood changes, depression, suicidal thoughts)

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Resolor, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Resolor should not be used if:
• You are allergic to prucalopride or any of its ingredients;
• You have severe kidney problems that require hemodialysis;
• You have intestinal perforation or obstruction;
• You have severe inflammatory conditions such as Crohn's disease, ulcerative colitis, toxic megacolon

Tell your doctor about all of your medical conditions, past and present, before starting Resolor. Resolor should be used with caution in patients with any severe and clinically unstable medical conditions. Doctors often reduce dosages for patients over the age of 65. This is crucial because certain conditions can affect whether Resolor is right for you. These conditions may include, but are not limited to:
• Severe lung disease
• Severe neurological or psychiatric disorders
• Unstable cardiovascular disease

Drug Interactions:

Before taking Resolor, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the official Resolor prescribing information (package insert): https://pdf.hres.ca/dpd_pm/00050086.PDF.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. While Resolor generally has a low potential for drug interactions, it is crucial to provide your doctor with a complete list of all medications.

Pregnancy and Breastfeeding:

Resolor is contraindicated during pregnancy. Women of childbearing potential are advised to use effective contraception during treatment with Resolor. Consult your doctor or pharmacist before breastfeeding while taking Resolor, as it may pass into breast milk.

Lactose Intolerance:

Resolor tablets contain lactose. Patients with galactose intolerance, total lactase deficiency, or glucose-galactose malabsorption should not take this medicine. If you have lactose intolerance, talk to your doctor or pharmacist.

Frequently Asked Questions about Resolor at Canada Pharmacy Online:

Why is Resolor more affordable in Canada than in the United States?

Prescription drug prices, including Resolor, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

Can the Resolor tablet be split or crushed?

Do not crush, chew, or split Resolor tablets. Swallow the tablet whole with water. Crushing, chewing, or splitting the tablets may affect how the medication works. Consult your doctor or pharmacist if you have difficulty swallowing the tablet.

What is the difference between Resolor 1 mg and 2 mg?

The difference in dosage represents the amount of active ingredient(s) present in the drug.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many tablets I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Resolor at once, per your doctor's prescription.

Can I buy over the counter from you?

No, Resolor requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Resolor?

Yes, there is a generic alternative for this product called prucalopride succinate.

Blog Post

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News

Gut microbiota: The pivotal conduit in the onset of constipation and its alleviation by tea flower polysaccharides (TFP) in a mouse model (study published on February 7, 2025)

The generic alternative is not manufactured by the company that makes the brand product.

Similar Drugs in the category of Laxatives & Antidiarrhea:

Motegrity Imodium Lactulose Resotran Normacol

This information is for general knowledge only and not medical advice. Always consult a qualified doctor, pharmacist, or other qualified healthcare provider for personalized medical guidance, diagnosis, or treatment. Information on this page is provided by independent third parties; CanadaPharmacyOnline cannot guarantee its medical accuracy.

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