Resotran (Prucalopride Succinate)

Name: Resotran
Brand: Amdipharm
SKU: 6836
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Resotran

Manufacturer: Amdipharm

Country: Canada

Dosage: 1 mg

Qty-Price (USD):

Type:

Product: Resotran

Manufacturer: Amdipharm

Country: Canada

Dosage: 2 mg

Qty-Price (USD):

Generic Equivalent of Resotran

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Prucalopride Succinate

Manufacturer: Generic

Country: Canada

Dosage: 1 mg

Qty-Price (USD):

Type:

Product: Prucalopride Succinate

Manufacturer: Generic

Country: Canada

Dosage: 2 mg

Qty-Price (USD):

Resotran Information

medically reviewed by Carol Hou (BSc. Pharm) on April 28, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Resotran and Prucalopride Succinate at CanadaPharmacyOnline.com

Prucalopride succinate is marketed under various brand names, including Resolor, Motegrity, and Resotran, and the distribution rights vary by country. Brand Resotran (prucalopride Succinate) is manufactured by Janssen Inc. and distributed by Amdipharm in Canada. In the United States, prucalopride is marketed as Motegrity by Takeda Pharmaceuticals. Pharmaceutical distribution and marketing rights are subject to change; verify information with official regulatory sources.

Generic prucalopride succinate is sourced from manufacturers meeting applicable local regulatory standards. The specific manufacturer of dispensed medication may vary.

Important Information about Generic Prucalopride Succinate:

Generic prucalopride succinate contains the same active ingredient as brand-name Resotran and is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as Resotran. Studies have demonstrated bioequivalence between generic and brand-name prucalopride succinate, meaning they have comparable absorption rates and overall effects. However, individual responses to any medication can vary. Talk to your doctor or pharmacist, if you have any questions about using generic prucalopride succinate. For more information about generic drug approval and bioequivalence, you can visit the FDA website: https://www.fda.gov/drugs/buying-using-medicine-safely/generic-drugs

Dosage:

Brand Resotran and generic prucalopride succinate are available in 1 and 2 mg oral tablets.

Your doctor will determine the appropriate dose based on your needs and medical conditions.

Usage:

Resotran (prucalopride succinate) is a prescription medication used for the treatment of chronic idiopathic constipation (CIC) in adults for whom laxatives do not work well enough. (source: product monograph)

Mechanism of Action Prucalopride Succinate is in a class of medications called serotonin receptor agonists, specifically a highly selective 5-HT4 receptor agonist. It works by stimulating 5-HT4 receptors in the gastrointestinal tract, enhancing colonic motility and increasing the rhythmic contractions of the colon muscles. These contractions help to move stool through the colon, thereby relieving constipation.

Take Resotran orally exactly as your doctor prescribes, following the instructions in the patient information leaflet accompanying the medication. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Resotran, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects

The information below outlines potential side effects associated with Resotran. It is not an exhaustive list, and individual reactions can vary. Before starting Resotran, it is crucial to discuss possible side effects and risks with your doctor or pharmacist.

Common side effects - These are some common side effects of Resotran, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning or if you experience any other concerning symptoms.
• Abdominal pain;
• Decreased appetite;
• Diarrhea (if you experience severe or persistent diarrhea, contact your doctor immediately);
• Dizziness;
• Dyspepsia;
• Fatigue;
• Flatulence;
• Headache;
• Increased bowel sounds;
• Nausea;
• Vomiting

Serious or rare side effects- Stop taking Resotran and seek immediate medical attention or call emergency services if you experience any of the following:
• Allergic reaction (angioedema, hives, and shortness of breath)
• Heart rhythm issues (palpitations, irregular heartbeat, and rarely, atrial fibrillation)
• Rare mental health changes (mood changes, depression, suicidal thoughts)

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Resotran, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Resotran should not be used if:
• You are allergic to prucalopride or any of its ingredients;
• You have severe kidney problems that require dialysis;
• You have intestinal perforation or obstruction;
• You have severe inflammatory bowel disease (Crohn's disease, ulcerative colitis, toxic megacolon)

Tell your doctor about all of your medical conditions, past and present, before starting Resotran. Resotran should be used with caution in patients with any severe and clinically unstable medical conditions. Dosage adjustments may be necessary for patients over 65. This is crucial because certain conditions can affect whether Resotran is right for you. These conditions may include, but are not limited to:
• Severe lung disease;
• Severe neurological or psychiatric disorders;
• Unstable cardiovascular disease

Drug Interactions:

Before taking Resotran, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the official Resotran prescribing information (package insert): https://pdf.hres.ca/dpd_pm/00026353.PDF.

While Resotran generally has a low potential for drug interactions, it is crucial to provide your doctor with a complete list of all medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements.

Pregnancy and Breastfeeding:

Prucalopride (Resotran) is not recommended during pregnancy due to limited data on its safety in pregnant women. Women of childbearing potential are strongly advised to use effective contraception during treatment with prucalopride. Prucalopride is excreted in human milk, and while studies suggest levels are low at typical doses, the clinical significance for the breastfed infant is not fully established. Caution is advised when breastfeeding while taking prucalopride (Resotran), and the decision to breastfeed should be made in consultation with your doctor, considering the benefits of breastfeeding for the infant and the necessity of treatment for the mother. Always consult a doctor if you are pregnant or breastfeeding before taking prucalopride (Resotran).

Lactose Intolerance:

Resotran tablets contain lactose. Do not take this medication if you have galactose intolerance, total lactase deficiency, or glucose-galactose malabsorption. If you have lactose intolerance, talk to your doctor or pharmacist.

Frequently Asked Questions about Resotran at Canada Pharmacy Online:

Why is Resotran more affordable in Canada than in the United States?

Prescription drug prices, including Resotran, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

Can the Resotran tablet be split or crushed?

Do not crush, chew, or split Resotran tablets. Swallow the tablet whole with water. Crushing, chewing, or splitting the tablets may affect how the medication works. Consult your doctor or pharmacist if you have difficulty swallowing the tablet.

What is the difference between Resotran 1 mg and 2 mg?

The difference in dosage represents the amount of active ingredient(s) present in the drug.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many tablets I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Resotran at once, per your doctor's prescription.

Can I buy over the counter from you?

No, Resotran requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Resotran?

Yes, there is a generic alternative for this product called prucalopride succinate.

Blog Post

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News

Most Patients Visiting EDs for Chronic Constipation Not on Appropriate Meds (article published on March 27, 2025)

The generic alternative is not manufactured by the company that makes the brand product.

Similar Drugs in the category of Laxatives & Antidiarrhea:

Motegrity Resolor Imodium Lactulose Normacol

This information is for general knowledge only and not medical advice. Always consult a qualified doctor, pharmacist, or other qualified healthcare provider for personalized medical guidance, diagnosis, or treatment. Information on this page is provided by independent third parties; CanadaPharmacyOnline cannot guarantee its medical accuracy.

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