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Spiriva Respimat (Tiotropium Bromide)

Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
Type: drug type
Product: Spiriva Respimat
Manufacturer: Boehringer Ingelheim
Country: Canada
Dosage: 2.5 mcg/4 ml/60 puffs
Qty-Price (USD):
Type: drug type
Product: Spiriva Respimat
Manufacturer: Boehringer Ingelheim
Country: Australia
Dosage: 2.5 mcg/60 puffs
Qty-Price (USD):
Type: drug type
Product: Spiriva Respimat
Manufacturer: Boehringer Ingelheim
Country: New Zealand
Dosage: 2.5 mcg/60 puffs
Qty-Price (USD):

Generic Equivalent of Spiriva Respimat
Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
There is no generic product of Spiriva Respimat.

Spiriva Respimat Information

portrait medically reviewed by Carol Hou (BSc. Pharm) on June 23, 2025.
A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

SPIRIVA RESPIMAT at CanadaPharmacyOnline.com

The brand name SPIRIVA RESPIMAT (tiotropium bromide inhalation solution) is manufactured by Boehringer Ingelheim and is available in various countries, including Canada, Australia, and New Zealand.

The generic version of SPIRIVA RESPIMAT is currently unavailable (at this pharmacy).

Dosage:

Brand SPIRIVA RESPIMAT, a soft mist inhaler (SMI), is available in strengths such as 2.5 mcg per actuation with 60 actuations per inhaler. This inhaler delivers 2.5 mcg of tiotropium per puff and contains enough solution for 60 actuations. The total amount of tiotropium delivered by the inhaler is 150 mcg (60 puffs x 2.5 mcg/puff). The total amount of tiotropium bromide monohydrate in the inhaler is approximately 0.187 mg.

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

SPIRIVA RESPIMAT (tiotropium bromide inhalation solution) is a long-term, once-daily prescription medication used for the maintenance treatment to control symptoms of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. And to reduce the frequency of COPD exacerbations. SPIRIVA RESPIMAT is also used as an add-on maintenance treatment for asthma in patients aged 6 years and older who remain symptomatic on inhaled corticosteroids and long-acting beta-agonists. SPIRIVA RESPIMAT is a maintenance medication and should be used regularly, even if you are feeling well. It is not a rescue inhaler and will not immediately relieve sudden breathing problems.

Mechanism of Action:
SPIRIVA RESPIMAT contains tiotropium bromide, a long-acting muscarinic antagonist (LAMA) that primarily blocks M3 receptors in the airways. This action prevents acetylcholine-induced bronchoconstriction, leading to bronchodilation and improved airflow in patients with chronic obstructive pulmonary disease (COPD) and as an add-on maintenance treatment for some patients with asthma. The Respimat inhaler delivers tiotropium bromide directly to the lungs as a slow-moving mist, enhancing drug delivery. Once inhaled, tiotropium competitively and reversibly binds to M3 muscarinic receptors in the airway smooth muscle. Acetylcholine, released from parasympathetic nerve endings, normally binds to these receptors, causing smooth muscle contraction (bronchoconstriction). By blocking the binding of acetylcholine, SPIRIVA RESPIMAT causes the airway smooth muscle to relax and widen (bronchodilation), making breathing easier. This helps to relieve symptoms of COPD and, in specific cases, asthma. While anticholinergics can affect mucus secretion by acting on muscarinic receptors on submucosal glands, this is not a primary clinical effect of tiotropium in managing COPD or asthma.

Use SPIRIVA RESPIMAT exactly as your doctor prescribes, following the instructions in the Canadian product monograph. Always consult your doctor for personalized guidance and to ensure safe and effective use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking SPIRIVA RESPIMAT, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects associated with SPIRIVA RESPIMAT (tiotropium bromide inhalation solution). It is not an exhaustive list, and individual reactions can vary.

Common side effects—These are some common side effects of SPIRIVA RESPIMAT. They are generally mild and may go away as your body adjusts to the medication, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.

The most common side effects include:
• Cough
• Dizziness
• Dry mouth
• Headache
• Indigestion
• Possible mild and transient increase in cough or throat irritation
• Runny nose
• Sinus infection
• Sore throat

Serious Side Effects: These are rare but potentially severe side effects. Seek immediate medical attention or call emergency services if you experience any of the following:
• Acute narrow-angle glaucoma: Increased pressure in the eye with symptoms like eye pain, blurred vision, and seeing halos around lights.
• Allergic reactions: Symptoms can include hives, itching, rash, and/or swelling of the lips, tongue, or throat that may cause difficulty breathing or swallowing.
• Bronchospasm: Sudden worsening of breathing.
• Chest pain;
• Urinary retention: Difficulty passing urine or painful urination.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting SPIRIVA RESPIMAT, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

SPIRIVA RESPIMAT should not be used if:
• You have a known hypersensitivity reaction to tiotropium or any other component of the SPIRIVA RESPIMAT product. Symptoms of an allergic reaction can include hives, itching, rash, swelling of the lips, tongue, or throat, difficulty breathing or swallowing.
• You have a known history of hypersensitivity to tiotropium, atropine, or other anticholinergic drugs, including ipratropium, as cross-reactivity may occur. Your doctor will assess the risks and benefits.
• You need a rescue medication for sudden breathing problems. SPIRIVA RESPIMAT is a long-term maintenance treatment and not a rescue inhaler.
• You are under 6 years of age. The safety and effectiveness of SPIRIVA RESPIMAT have been established for the maintenance treatment of asthma in patients aged 6 years and older who remain symptomatic on inhaled corticosteroids and long-acting beta-agonists. Its use in children younger than 6 years with asthma and its use in children with COPD have not been established.

Tell your doctor about all of your medical conditions, past and present, before starting SPIRIVA RESPIMAT. This is crucial because certain conditions can affect whether SPIRIVA RESPIMAT is right for you. These conditions may include, but are not limited to:
• Moderate to severe renal impairment: These patients may be more susceptible to anticholinergic side effects.
• Narrow-angle glaucoma: It may worsen this condition.
• Urinary retention: It may worsen symptoms, especially in men with prostatic hyperplasia or bladder-neck obstruction.

Drug Interactions:

Before taking Spiriva Respimat, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the Spiriva Respimat prescribing information: https://patient.boehringer-ingelheim.com/us/products/spiriva/bipdf/spiriva-respimat-prescribing-information#page=1

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. It is also important to inform your doctor about any herbal teas, recreational drugs, or significant dietary changes you are making, as these could potentially interact with Spiriva Respimat. Spiriva Respimat may interact with other medicines but is not limited to:
• Atropine and its derivatives
• Certain antihistamines (e.g., diphenhydramine, chlorpheniramine)
• Certain antidepressants (e.g., tricyclic antidepressants like amitriptyline, desipramine)
• Certain antipsychotics (e.g., chlorpromazine, clozapine)
• Certain Parkinson's disease medications (e.g., benztropine, trihexyphenidyl)
• Glucagon: This medication, sometimes used for very low blood sugar, can increase the risk of stomach problems if taken with Spiriva.
• Medications for overactive bladder (e.g., oxybutynin, solifenacin, fesoterodine)
• Other anticholinergic bronchodilators (e.g., aclidinium, glycopyrrolate, ipratropium, umeclidinium, revefenacin)
• Potassium chloride and potassium citrate

Pregnancy and Breastfeeding:

Use of SPIRIVA RESPIMAT during pregnancy should be avoided unless the benefits outweigh the risks due to limited human data and findings in some animal studies of potential developmental toxicity at high doses. Limited data suggest that tiotropium bromide is likely present in breast milk at very low levels due to poor systemic absorption after inhalation. International guidelines generally suggest that breastfeeding can likely continue while using SPIRIVA RESPIMAT, considering the low potential risk to the infant. However, the benefits of breastfeeding and the mother's need for SPIRIVA RESPIMAT should always be considered, and a healthcare professional should be consulted for personalized advice. Always consult your doctor for personalized advice during pregnancy and breastfeeding.

Frequently Asked Questions about SPIRIVA RESPIMAT at Canada Pharmacy Online:

Why is SPIRIVA RESPIMAT more affordable in Canada than in the United States?

Prescription drug prices, including SPIRIVA RESPIMAT, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many SPIRIVA RESPIMAT I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of SPIRIVA RESPIMAT at once, per your doctor's prescription.

Can I buy over the counter from you?

No, SPIRIVA RESPIMAT requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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Prescriptions Dispensed from Canada are Dispensed by Candrug Pharmacy #18985. 202A 8322-130th Street, Surrey, British Columbia, Canada V3W 8J9, 604-543-8711. Pharmacy Manager: Carol Hou.
This pharmacy is duly licensed in the province of British Columbia, Canada by the College of Pharmacists of BC. If you have any questions or concerns you can contact the college at: 200-1765 West 8th Ave Vancouver, BC V6J 5C6 Canada.
All prices are in US dollars.
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