Vraylar (Cariprazine)

Name: Vraylar
Brand: Abbvie
SKU: 7684
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Vraylar Capsule

Manufacturer: Abbvie

Country: Canada

Dosage: 1.5 mg

Qty-Price (USD):

Type:

Product: Vraylar Capsule

Manufacturer: Gedeon Richter

Country: Australia

Dosage: 1.5 mg

Qty-Price (USD):

Type:

Product: Vraylar Capsule

Manufacturer: Recordati Pharma

Country: United Kingdom

Dosage: 1.5 mg

Qty-Price (USD):

Type:

Product: Vraylar Capsule

Manufacturer: Abbvie

Country: Canada

Dosage: 3 mg

Qty-Price (USD):

Type:

Product: Vraylar Capsule

Manufacturer: Gedeon Richter

Country: Australia

Dosage: 3 mg

Qty-Price (USD):

Type:

Product: Vraylar Capsule

Manufacturer: Recordati Pharma

Country: United Kingdom

Dosage: 3 mg

Qty-Price (USD):

Type:

Product: Vraylar Capsule

Manufacturer: Abbvie

Country: Canada

Dosage: 4.5 mg

Qty-Price (USD):

Type:

Product: Vraylar Capsule

Manufacturer: Gedeon Richter

Country: Australia

Dosage: 4.5 mg

Qty-Price (USD):

Type:

Product: Vraylar Capsule

Manufacturer: Recordati Pharma

Country: United Kingdom

Dosage: 4.5 mg

Qty-Price (USD):

Type:

Product: Vraylar Capsule

Manufacturer: Gedeon Richter

Country: Australia

Dosage: 6 mg

Qty-Price (USD):

Type:

Product: Vraylar Capsule

Manufacturer: Recordati Pharma

Country: United Kingdom

Dosage: 6 mg

Qty-Price (USD):

Generic Equivalent of Vraylar

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Cariprazine Capsule

Manufacturer: Generic

Country: India

Dosage: 1.5 mg

Qty-Price (USD):

Type:

Product: Cariprazine Capsule

Manufacturer: Generic

Country: India

Dosage: 3 mg

Qty-Price (USD):

Type:

Product: Cariprazine Capsule

Manufacturer: Generic

Country: India

Dosage: 4.5 mg

Qty-Price (USD):

Type:

Product: Cariprazine Capsule

Manufacturer: Generic

Country: India

Dosage: 6 mg

Qty-Price (USD):

Vraylar Information

medically reviewed by Carol Hou (BSc. Pharm) on April 30, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

VRAYLAR and Cariprazine at CanadaPharmacyOnline.com

Brand VRAYLAR (cariprazine) is manufactured by AbbVie and is available in many countries worldwide, including Canada. The brand VRAYLAR (cariprazine) is marketed as Reagila (cariprazine) and is manufactured by Gedeon Richter for markets outside of North America, including Australia. Recordati Pharma markets Reagila in the United Kingdom.

Generic cariprazine is sourced from manufacturers meeting applicable local regulatory standards for safety, efficacy, and quality. The specific manufacturer of dispensed medication may vary.

Important Information about Generic Cariprazine:

Generic cariprazine contains the same active ingredient as brand-name VRAYLAR and is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as VRAYLAR. Studies have demonstrated bioequivalence between generic and brand-name cariprazine, meaning they have comparable absorption rates and overall effects. However, individual responses to any medication can vary. Talk to your doctor or pharmacist, if you have any questions about using generic cariprazine.

For more information about generic drug approval and bioequivalence, you can visit the FDA website: https://www.fda.gov/drugs/buying-using-medicine-safely/generic-drugs

Dosage:

Brand VRAYLAR and generic cariprazine are commonly available in 1.5 mg, 3 mg, 4.5 mg, and 6 mg oral capsules.

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

VRAYLAR (cariprazine) is a prescription medication used for schizophrenia, acute treatment of manic or mixed episodes, and depressive episodes due to bipolar 1 disorder in adults. VRAYLAR is also used as an add-on treatment to antidepressant medications for major depressive disorder (MDD) in adults. (source: the product labeling information)

Mechanism of Action:
Cariprazine, an atypical (second-generation) antipsychotic, exerts its effects by modulating dopamine and serotonin neurotransmission. It primarily acts as a partial agonist at dopamine D3 receptors, with a higher binding affinity for D3 than D2 receptors. It also acts as a partial agonist at serotonin 5-HT1A receptors and as an antagonist at serotonin 5-HT2A receptors. This partial agonism allows cariprazine to either increase or decrease receptor activity depending on the baseline neurotransmitter levels. The high D3 receptor affinity, combined with 5-HT1A partial agonism and 5-HT2A antagonism, contributes to its therapeutic effects in schizophrenia, bipolar disorder, and major depressive disorder. (source: National Library of Medicine)

Take VRAYLAR exactly as your doctor prescribes, following the instructions in the patient information leaflet accompanying the medication. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking VRAYLAR, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects associated with VRAYLAR (cariprazine). It is not an exhaustive list, and individual reactions can vary. This information is for educational purposes and should not replace professional medical advice. Before starting VRAYLAR, it is crucial to discuss possible side effects and risks with your doctor or pharmacist.

Common side effects - These are some common side effects of VRAYLAR, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning or if you experience any other concerning symptoms.
• Dizziness;
• Gastrointestinal issues (constipation, nausea, indigestion, vomiting);
• Headache;
• Increased appetite;
• Insomnia (trouble sleeping);
• Extrapyramidal symptoms (EPS) including akathisia (restlessness), parkinsonism (tremors, slow movements, rigidity), dystonia (sustained muscle contractions), and tardive dyskinesia (TD) (uncontrolled muscle movements);
• Somnolence (sleepiness or drowsiness)

Serious or rare side effects- Stop taking VRAYLAR and seek immediate medical attention or call emergency services if you experience any of the following:
• Allergic reaction including rash, itching, swelling, severe dizziness, and trouble breathing;
• Increased risk of death in elderly people with dementia-related psychosis (VRAYLAR is associated with an increased risk of death in elderly patients with dementia-related psychosis);
• Leukopenia/Neutropenia (low white blood cell counts, which can increase the risk of infection);
• Metabolic changes (hyperglycemia (high blood sugar), hyperlipidemia (high cholesterol and triglycerides), weight gain);
• Neuroleptic malignant syndrome (NMS) (a life-threatening condition, symptoms include high fever, stiff muscles, confusion, increased sweating, and changes in breathing, heart rate, and blood pressure);
• Orthostatic hypotension (drop in blood pressure when standing, causing dizziness and Fainting, which can increase the risk of falls);
• Seizures;
• Tardive dyskinesia (TD) (uncontrolled and potentially irreversible movements of the face, tongue, and other body parts);
• Thoughts of suicide or self-harm, or worsening depression

Contraindications:

The following is not an exhaustive list of contraindications. Before starting VRAYLAR, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

VRAYLAR should not be used if:
• You are allergic to cariprazine or any of its ingredients;
• You are elderly patient with dementia-related psychosis, due to an increased risk of mortality, VRAYLAR is not approved to treat dementia related psychosis;
• You have severe hepatic impairment (Child-Pugh Class C);
• You have severe renal impairment (estimated creatinine clearance less than 30 mL/minute).

Tell your doctor about all of your medical conditions, past and present, before starting VRAYLAR. This is crucial because certain conditions can affect whether VRAYLAR is right for you. These conditions may include, but are not limited to:
• Cardiovascular problems (heart disease, high blood pressure, irregular heart rhythms, or a history of stroke, and QT prolongation);
• History of Neuroleptic malignant syndrome (NMS);
• Impaired ability to regulate core body temperature;
• Liver or kidney problems;
• Mental health conditions (including any history of psychosis, bipolar disorder, depression, or other mental health problems, especially any history of suicidal thoughts and behaviors);
• Movement disorders (Parkinson's disease or tardive dyskinesia);
• Seizure disorders (epilepsy or a history of seizures)

Drug Interactions:

Before taking VRAYLAR, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the official VRAYLAR prescribing information (package insert): https://www.rxabbvie.com/pdf/VRAYLAR_pi.pdf

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. VRAYLAR may interact with other medicines but is not limited to:
• Benzodiazepines (increased risk of sedation and other side effects);
• Blood pressure medications (potential for interactions due to VRAYLAR's effect on blood pressure);
• Strong CYP3A4 Inducers (e.g., carbamazepine, phenytoin, rifampin, St. John's wort) which can significantly decrease VRAYLAR levels;
• Strong CYP3A4 Inhibitors (e.g., ketoconazole, itraconazole, clarithromycin) which can significantly increase VRAYLAR levels;
• Strong CYP2D6 inhibitors (e.g. fluoxetine, paroxetine) which can increase VRAYLAR levels.
• MAOIs (potential for increased adverse effects);
• Other antipsychotics (increased risk of side effects);
• Seizure medications (potential for interactions affecting VRAYLAR levels);
• Tricyclic antidepressants (TCAs) (potential for increased side effects)

Alcohol and Grapefruit
Avoid or limit alcohol consumption while taking VRAYLAR. Mixing VRAYLAR and alcohol can increase the risk of side effects. Alcohol can interfere with the effectiveness of VRAYLAR and worsen the symptoms of the mental health condition it's intended to treat. Individual reactions can vary and its interaction with VRAYLAR can be unpredictable. Grapefruit and grapefruit juice can inhibit the CYP3A4 enzyme in the body, which can increase the levels of VRAYLAR in your blood stream increasing the risk of side effects.

Dizziness and Drowsiness:
VRAYLAR may cause dizziness or drowsiness. Avoid driving, operating machinery, or engaging in activities that require alertness until you understand how it affects you.

Pregnancy and Breastfeeding:

VRAYLAR's safety during pregnancy and breastfeeding is uncertain. You must consult with your doctor to discuss the potential risks and benefits before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.

Frequently Asked Questions about VRAYLAR at Canada Pharmacy Online:

Why is VRAYLAR more affordable in Canada than in the United States?

Prescription drug prices, including VRAYLAR, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

Can the VRAYLAR pill be split or crushed?

Do not crush, chew, or split VRAYLAR capsules. Swallow the capsule whole with water. Crushing, chewing, or splitting the capsules may affect how the medication is released and absorbed in the body. Consult your doctor or pharmacist if you have difficulty swallowing the capsule.

What is the difference between VRAYLAR 1.5 mg and 3 mg?

The difference in dosage represents the amount of active ingredient(s) present in the drug.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many capsules I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of VRAYLAR at once, per your doctor's prescription.

Can I buy over the counter from you?

No, VRAYLAR requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for VRAYLAR?

Yes, there is a generic alternative for this product called cariprazine.

Blog Posts

10 Awesome Gifts for Improving Mental Health and Happiness
Why Ethnic Minorities Suffer with Worse Mental Health
Infertility Affects the Mental Health of Women and Men
Binge-Watching Netflix Could Impact Your Mental Health
How to Find a Good Psychiatrist

News

Genetic and environmental factors in schizophrenia (article published on March 26, 2025)

Similar Drugs in the category of Psychiatric Medication:

Latuda Abilify Seroquel Saphris Rexulti

The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

Reviews From Real Customers