Zomig (Zolmitriptan)

Name: Zomig
Brand: AstraZeneca
SKU: 2262
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Zomig Tablet

Manufacturer: AstraZeneca

Country: Australia

Dosage: 2.5 mg

Qty-Price (USD):

Generic Equivalent of Zomig

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Zolmitriptan Tablet

Manufacturer: Generic

Country: Canada

Dosage: 2.5 mg

Qty-Price (USD):

Zomig Information

medically reviewed by Dr. HaVy Ngo, Pharmacist on November 19, 2025.

Zomig and Zolmitriptan at CanadaPharmacyOnline.com

Zomig is the brand name for the migraine drug zolmitriptan. AstraZeneca originally developed it and is available in different countries, including Australia.

Generic zolmitriptan is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Zolmitriptan:

Generic zolmitriptan contains the same active ingredient as the brand-name Zomig and must meet the same safety, effectiveness, and quality standards as the brand-name product. This means it’s designed to work in the same way as zolmitriptan. Studies have demonstrated bioequivalence between generic and brand-name zolmitriptan, meaning they have comparable absorption rates and overall effects. However, individual responses to any medication can vary. If you have any questions about using generic Zolmitriptan, talk to your doctor or pharmacist.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage:

Zomig and its generic form, zolmitriptan, are available as oral tablets in 2.5 mg strengths.

Zomig is also available in other formulations, such as Zomig Nasal Spray and Zomig Rapimelt ZMT.

Your doctor will determine the appropriate dose based on your individual needs and medical history.

Usage:

Zomig (zolmitriptan) is a prescription medication used for the acute treatment of migraine headaches. Not only does it relieve the throbbing pain, but it also helps alleviate associated symptoms such as nausea and sensitivity to light and sound.

Mechanism of Action
Zomig (zolmitriptan) mainly works by targeting specific serotonin receptors (5-HT) in the brain, specifically the 5-HT1B and 5-HT1D receptors. When you take Zomig, it functions like a natural pain regulator by activating these receptors, leading to a dual action that stops the migraine. First, it causes the abnormally dilated blood vessels around the brain to constrict, reducing the pressure that contributes to the throbbing pain. Second, it prevents the release of pain-causing inflammatory chemicals (such as CGRP) from nerve endings in the head, thereby preventing the pain signal from fully developing. This combination of effects allows Zomig to relieve head pain and other migraine symptoms quickly.

Take Zomig exactly as your doctor prescribes, following the instructions in the product monograph in Canada. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Zomig, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below is a partial list of side effects; individual reactions can vary. Before starting Zomig, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common Side Effects – The following are some common side effects of Zomig; other side effects may also occur. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Asthenia (lack or loss of strength)
• Dizziness or faintness
• Drowsiness or sleepiness
• Dry mouth
• Nausea
• Neck/throat/jaw pain, pressure, or tightness
• Paresthesia (tingling, "pins and needles," or numbness)
• Pressure or heavy feeling in any part of the body (e.g., chest, neck)
• Warm/cold sensations
• Weakness

Other Potential Side Effects (less common):
• Diarrhea
• Dyspepsia (indigestion)
• Dysphagia (difficulty swallowing)
• Palpitations (fast or pounding heartbeat)
• Vertigo (sensation of spinning)

Serious Side Effects – These are rare but potentially severe side effects of Zomig. Seek immediate medical attention or call emergency services if you experience any of the following:
• Cerebrovascular events (stroke or bleeding in the brain)
• Coronary artery vasospasm (sudden narrowing of heart arteries)
• Gastrointestinal or Splenic Ischemic Events (lack of blood flow to the gut or spleen, potentially causing severe abdominal pain and bloody diarrhea)
• High blood pressure (significant increase)
• Hypersensitivity reactions (including angioedema—swelling of the face, tongue, or throat
• Medication Overuse Headache (MOH)
• Myocardial infarction (heart attack)
• Serotonin syndrome (symptoms may include agitation, fever, rapid heart rate, and severe nausea/diarrhea)

Contraindications

The following is not an exhaustive list of contraindications. Before starting Zomig, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Zomig (zolmitriptan) should NOT be used if any of the following apply to you.

Cardiovascular and Blood Vessel Issues
• Any history of stroke or transient ischemic attack (TIA).
• Coronary artery vasospasm (Prinzmetal's angina).
• Ischemic heart disease (e.g., angina, history of heart attack).
• Peripheral vascular disease (PVD) or ischemic bowel disease. (The drug affects blood vessels everywhere.)
• Uncontrolled high blood pressure (hypertension).
• Wolff-Parkinson-White Syndrome or other dangerous irregular heart rhythms.

Drug Interaction Conflicts
• You have taken another triptan or an ergot-type medication (like ergotamine) within the last 24 hours. (Do not mix vasoconstrictors!)
• You have taken an MAO-A inhibitor in the past two weeks (14 days).

Migraine Type and Allergy
• You have basilar or hemiplegic migraine. (Triptans are often risky for these types.)
• You have an allergy to zolmitriptan or any of the product's ingredients.

Tell your doctor about all of your medical conditions, past and present, before starting Zomig. This is crucial because certain conditions affect whether Zomig is right for you. These conditions may include, but are not limited to:
• Liver disease (moderate to severe)
• Multiple cardiovascular risk factors (e.g., smoking, obesity, diabetes, high cholesterol, postmenopausal women, men over 40)
• Phenylketonuria (PKU), as the orally disintegrating tablet (Zomig-ZMT) contains phenylalanine
• Current or recent use of Serotonin-Affecting Antidepressants (SSRIs/SNRIs), due to the heightened risk of Serotonin Syndrome. (This risk requires close monitoring.)

Drug Interactions

Before taking Zomig, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, visit the highlights of prescribing information from DailyMed (.gov) at https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=f2073122-5138-41ba-b791-a9b088bb98b7&type=display.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Zomig may interact with other medicines, but is not limited to:

Do NOT Mix (Must Be Separated)
These combinations can cause severe, life-threatening cardiovascular problems (vasospasm) or dangerously high drug levels.
• Other Triptans (5-HT Agonists): (e.g., sumatriptan, rizatriptan): Do not use within 24 hours of taking Zomig. Due to an Increased risk of severe vasospasm and cardiovascular events.
• Ergot-Type Medications: (e.g., ergotamine, dihydroergotamine): Do not use within 24 hours of taking Zomig. Due to a high risk of prolonged, severe vasospasm (blood vessel narrowing).
• MAO Inhibitors (MAOIs): (e.g., phenelzine, tranylcypromine): Do not use Zomig if you have taken an MAO inhibitor within the past 14 days (2 weeks). Due to significantly increased Zomig blood levels, there is a risk of serious side effects.

High Risk of Serotonin Syndrome (Requires Close Monitoring)
Combining Zomig with these drugs can lead to Serotonin Syndrome, a serious condition affecting the nervous system.
• SSRIs (e.g., fluoxetine, sertraline)
• SNRIs (e.g., duloxetine, venlafaxine)
• Tricyclic Antidepressants (e.g., amitriptyline)
• St. John's Wort (Herbal Supplement): It requires close monitoring by a doctor, especially when starting or increasing the dose of either medication.

Dose Adjustments Required (Limit Zomig to 5 mg/day)
These medications can slow the breakdown of Zomig, increasing its concentration in your body.
• Cimetidine (Tagamet)
• Quinolone Antibiotics (e.g., ciprofloxacin, levofloxacin): If used together, the maximum daily dose of Zomig must be limited to 5 mg per day.

Pregnancy and Breastfeeding

Always consult your healthcare provider before using Zomig (zolmitriptan) if you are pregnant or breastfeeding, as there is limited conclusive human safety data.
• During Pregnancy: Zolmitriptan is typically only recommended if the benefits of treating severe migraine clearly outweigh the potential risks to the fetus, especially since some animal studies have shown possible adverse effects.
• While Breastfeeding: Only small amounts of zolmitriptan are thought to pass into breast milk, suggesting a low risk to the infant. However, many healthcare providers will recommend an extra layer of caution by either:
o Suggesting alternative triptans (like sumatriptan) that have more established safety profiles.
o Advising you to avoid breastfeeding for 24 hours after taking a dose to minimize infant exposure.

Use in the Elderly

Zomig (zolmitriptan) is generally not recommended for older adults aged 65 and older. Since the safety and effectiveness haven't been established, and because this age group is at a higher risk for uncontrolled high blood pressure and heart problems (absolute contraindications for all triptans), your doctor must perform a thorough cardiovascular evaluation before considering Zomig.

Use in Children

Zomig Oral Tablets and Zomig Rapimelt (oral disintegrating tablets) are generally not approved for use in individuals under 18 years of age.

Frequently Asked Questions about Zomig at Canada Pharmacy Online:

Why is Zomig more affordable in Canada than in the United States?

Prescription drug prices, including Zomig, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is committed to providing you with the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on the number of tablets I can order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Zomig at a time, as per your doctor's prescription.

Can I buy over the counter from you?

No, Zomig Rapimelt requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days for your order to be delivered from our pharmacy.

Blog Posts:

Suffering From Migraines? Make Sure You’re Not Deficient in This Important Mineral
Which Triptan Should I Choose for Migraine Relief?

Latest News:

Weather changes can be a pain, literally, for migraine sufferers (article published on November 6, 2025)

Similar Drugs in the category of Migraine Medication:

Imitrex Frova Relpax Maxalt Zomig Nasal Spray

The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

Reviews From Real Customers