Aceon (Perindopril Erbumine)

Name: Aceon
Brand: Servier
SKU: 0010
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Aceon Tablet

Manufacturer: Servier

Country: Canada

Dosage: 2 mg

Qty-Price (USD):

Type:

Product: Aceon Tablet

Manufacturer: Serdia

Country: India

Dosage: 2 mg

Qty-Price (USD):

Type:

Product: Aceon Tablet

Manufacturer: Servier

Country: Canada

Dosage: 4 mg

Qty-Price (USD):

Type:

Product: Aceon Tablet

Manufacturer: Serdia

Country: India

Dosage: 4 mg

Qty-Price (USD):

Type:

Product: Aceon Tablet

Manufacturer: Servier

Country: Canada

Dosage: 8 mg

Qty-Price (USD):

Type:

Product: Aceon Tablet

Manufacturer: Serdia

Country: India

Dosage: 8 mg

Qty-Price (USD):

Type:

Product: Aceon Tablet

Manufacturer: Servier

Country: Turkey

Dosage: 10 mg

Qty-Price (USD):

Generic Equivalent of Aceon

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Perindopril Erbumine Tablet

Manufacturer: Generic

Country: Canada

Dosage: 2 mg

Qty-Price (USD):

Type:

Product: Perindopril Erbumine Tablet

Manufacturer: Generic

Country: Canada

Dosage: 4 mg

Qty-Price (USD):

Type:

Product: Perindopril Erbumine Tablet

Manufacturer: Generic

Country: Canada

Dosage: 8 mg

Qty-Price (USD):

Aceon Information

medically reviewed by Dr. HaVy Ngo, Pharmacist on April 25, 2025.

Aceon and Perindopril Erbumine at CanadaPharmacyOnline.com

The brand Aceon is primarily manufactured by Servier in Canada. Aceon is also available under brand name Coversyl, distributed by Serdia in India, Turkey, and other countries.

Generic perindopril erbumine is sourced from manufacturers that meet applicable safety standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Perindopril Erbumine:

Generic perindopril erbumine contains the same active ingredient as brand-name Aceon and is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as Aceon. Studies have demonstrated bioequivalence between generic and brand-name Aceon, meaning they have comparable absorption rates and overall effects. However, individual responses to any medication can vary. Talk to your doctor or pharmacist if you have any questions about using generic perindopril erbumine.

For more information about generic drug approval and bioequivalence, you can visit https://www.fda.gov/drugs/buying-using-medicine-safely/generic-drugs

Dosage:

The brand Aceon and generic perindopril erbumine are available in strengths of 2 mg, 4 mg, 8 mg, and 10 mg oral tablets.

Your doctor will determine your safe and effective dosage based on your individual needs.

Usage:

Aceon (perindopril erbumine) is a prescription medication used to lower blood pressure. It also helps protect against heart problems like strokes and heart attacks.

Mechanism of Action:
Aceon is an angiotensin-converting enzyme (ACE) inhibitor, and it exerts its therapeutic effects by competitively inhibiting ACE, thereby reducing the conversion of angiotensin I to angiotensin II. This inhibition leads to decreased levels of the potent vasoconstrictor angiotensin II, resulting in systemic vasodilation and a reduction in peripheral vascular resistance, ultimately lowering blood pressure. Reduced angiotensin II levels diminish aldosterone secretion from the adrenal cortex, leading to decreased sodium and water retention by the kidneys. ACE inhibition also results in increased levels of bradykinin, a vasodilator, which may contribute to the antihypertensive effects but is also implicated in certain side effects. By modulating the renin-angiotensin-aldosterone system, perindopril effectively manages hypertension and reduces cardiovascular risk in patients with stable coronary artery disease.

It is crucial to take Aceon exactly as your doctor prescribes and read the labelling information in Canada. Consult your doctor for personalized guidance and safe use.

Side Effects:

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Aceon, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Common Side Effects – These are some frequently reported side effects of Aceon, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or if you experience any other concerning symptoms.
• Cough (often dry and persistent)
• Dizziness
• Headache
• Fatigue
• Light-headedness
• Nausea

Serious Side Effects: Stop taking Aceon and seek immediate medical attention if you experience any of the following
• Angioedema: Swelling of the face, lips, tongue, or throat, which can cause difficulty breathing or swallowing. This is a medical emergency.
• Kidney problems: Changes in urination (decreased or increased), swelling in the legs or ankles.
• High potassium levels (hyperkalemia): Muscle weakness, numbness, tingling, slow heartbeat, or irregular heartbeat.
• Low blood pressure (hypotension): Severe dizziness, light-headedness, fainting, especially when standing up quickly.
• Allergic reactions: rash, itching, hives.
• Liver problems: Yellowing of the skin or eyes (jaundice), dark urine, pale stools, persistent stomach pain.

Contraindications:

The following is not an exhaustive list of contraindications. It is crucial to discuss all your medical conditions, past and present, and all the medications you are taking with your doctor or pharmacist before taking (perindopril erbumine).

Aceon (perindopril erbumine) is CONTRAINDICATED in the following situations and should not be used if:
• Hypersensitivity: Known hypersensitivity to perindopril or any other ACE inhibitor. This includes a history of angioedema (swelling of the face, lips, tongue, or throat) related to previous ACE inhibitor use.
• Hereditary or Idiopathic Angioedema: If you have a history of angioedema that was not caused by ACE inhibitors (either inherited or with no known cause), you should not take Aceon.
• Patient is diabetic with intentions on taking Aliskiren: Combining Aceon with aliskiren, another type of blood pressure medication that works on the renin-angiotensin-aldosterone system, is contraindicated in patients with diabetes or moderate to severe kidney disease due to an increased risk of adverse events such as kidney problems, high potassium levels (hyperkalemia), and low blood pressure.

Inform your doctor if you have any of the following pre-existing medical conditions, as they may affect whether Aceon is right for you:
• Kidney problems: Aceon can affect how your kidneys work, so your doctor might need to adjust your dose and check your kidneys regularly.
• Heart failure: If you have heart failure, your doctor will need to keep a close eye on you while you take Aceon.
• Dehydration: If you're losing fluids from vomiting, diarrhea, or taking water pills (diuretics), Aceon could make your blood pressure drop too low.
• Narrowed heart valves (aortic stenosis or mitral stenosis): If the valves in your heart are narrowed, Aceon could cause problems with blood flow.
• A history of swelling (angioedema), even if it wasn't from an ACE inhibitor: You might have a higher chance of swelling with Aceon.
• Dialysis: If you're on dialysis, your doctor will need to monitor you closely.
• Primary hyperaldosteronism: This is when your body makes too much of a certain hormone. Aceon usually doesn't work well for this condition.

Drug Interactions:

Before taking Aceon, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete information about potential drug interactions, consult the official Aceon product monograph: https://servier.ca/wp-content/uploads/sites/24/2022/11/Product-monograph-COVERSYL-PLUS.pdf?time=1669038047

The following is a list of potential drug interactions:
• Aliskiren: Concomitant use with aliskiren (another renin-angiotensin system inhibitor) is contraindicated in patients with diabetes mellitus or moderate to severe renal impairment due to an increased risk of adverse events such as kidney problems, high potassium, and low blood pressure. In other patients, avoid this combination if possible and monitor closely if used.
• Other ACE Inhibitors or Angiotensin Receptor Blockers (ARBs): Using Aceon with other ACE inhibitors (e.g., lisinopril, enalapril) or ARBs (e.g., losartan, valsartan) increases the risk of low blood pressure, kidney problems, and high potassium. This combination therapy should generally be avoided.
• Diuretics (Water Pills): Diuretics can increase the blood pressure-lowering effect of Aceon, potentially leading to excessive drops in blood pressure, especially when starting Aceon. Close monitoring is recommended.
• Nonsteroidal Anti-inflammatory Drugs (NSAIDs), including selective COX-2 inhibitors: NSAIDs (e.g., ibuprofen, naproxen) may reduce the blood pressure-lowering effect of ACE inhibitors. Additionally, the combination may increase the risk of kidney problems, especially in elderly patients or those with pre-existing kidney disease.
• Lithium: Aceon can increase lithium levels in the blood, potentially leading to lithium toxicity. Lithium levels should be monitored closely if these drugs are used together.
• Potassium-Sparing Diuretics (e.g., spironolactone, amiloride, triamterene) and Potassium Supplements: Aceon can increase potassium levels. Using it with potassium-sparing diuretics or potassium supplements can lead to hyperkalemia (high potassium), which can be serious.
• Insulin and Oral Antidiabetic Medications: ACE inhibitors can increase the sensitivity to insulin and may lead to hypoglycemia (low blood sugar) in diabetic patients. Close monitoring of blood glucose levels may be necessary.
• Gold (Sodium Aurothiomalate): Injectable gold used for arthritis has been associated with nitrotyrosine reactions (symptoms including flushing of the face, nausea, vomiting, and hypotension) when co-administered with ACE inhibitors.
• Sympathomimetics (e.g., pseudoephedrine, phenylephrine): These medications can counteract the blood pressure-lowering effect of Aceon. • mTOR inhibitors: Temsirolimus, sirolimus and, everolimus increase the risk of angioedema.
• Sacubitril/Valsartan: Due to the increased risk of angioedema, ACE inhibitors should generally not be used within 36 hours of switching to or from sacubitril/valsartan.

Pregnancy or Breastfeeding:

Aceon (perindopril erbumine) is contraindicated in the second and third trimesters of pregnancy due to the significant risk of fetal morbidity and mortality, including renal dysfunction, oligohydramnios, and skeletal deformities. If pregnancy is detected, Aceon should be discontinued immediately, and alternative antihypertensive therapy with established safety in pregnancy should be initiated. Breastfeeding while taking Aceon is generally not recommended as perindopril is excreted in breast milk, posing a potential risk of adverse effects, such as hypotension and electrolyte imbalances, in the nursing infant. Therefore, alternative medications with better-established safety profiles during lactation are preferred

Frequently Asked Questions about Aceon at Canada Pharmacy Online:

Why is Aceon more affordable in Canada than in the United States?

Prescription drug prices, including Aceon, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on getting you the lowest prices on high quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can place the order online or call Customer Service at 1866.920.3784. For additional information or to learn about the ordering process, visit our How to order page.

Is there a limit on how many Aceon tablets I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Aceon (perindopril erbumine) at one time, as per your doctor’s prescription.

Can I buy Aceon over the counter from you?

No, Aceon requires a valid prescription from your doctor. We are unable to sell this product without a valid prescription from your doctor.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Aceon?

Yes, there is a generic alternative for this product, called perindopril erbumine.

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This information is for general knowledge only and not medical advice. Always consult a qualified doctor, pharmacist, or other qualified healthcare provider for personalized medical guidance, diagnosis, or treatment. Information on this page is provided by independent third parties; CanadaPharmacyOnline cannot guarantee its medical accuracy.

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