Atripla (Efavirenz/Emtricitabine/Tenofovir)

Name: Atripla
Brand: Generic
SKU: 6651
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

There is no brand product of Atripla.

Generic Equivalent of Atripla

Type

Product

Manufacturer

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Qty-Price (USD)

Type:

Product: Efavirenz/Emtricitabine/Tenofovir (Vonavir-Emcure)

Manufacturer: Generic

Country: India

Dosage: 600 mg/200 mg/300 mg

Qty-Price (USD):

Type:

Product: Efavirenz/Emtricitabine/Tenofovir (Vonavir-Emcure) Tablet

Manufacturer: Generic

Country: India

Dosage: 600 mg/200 mg/300 mg

Qty-Price (USD):

Type:

Product: Efavirenz/Emtricitabine/Tenofovir Tablet

Manufacturer: Generic

Country: Canada

Dosage: 600 mg/200 mg/300 mg

Qty-Price (USD):

Atripla Information

medically reviewed by Dr. HaVy Ngo, Pharmacist on May 23, 2025.

Efavirenz/Emtricitabine/Tenofovir at CanadaPharmacyOnline.com

Brand Atripla is currently unavailable (at this pharmacy).

Generic efavirenz, emtricitabine, and tenofovir disoproxil fumarate are sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate:

Generic efavirenz, emtricitabine, and tenofovir disoproxil fumarate contain the same active ingredients as the brand name Atripla. It is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as Atripla. While specific bioequivalence studies are conducted to ensure generic medications have comparable absorption rates and overall effects, individual responses to any medication can vary. Talk to your doctor or pharmacist if you have questions about using generic efavirenz, emtricitabine, and tenofovir disoproxil fumarate. For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage:

The generic form of Atripla is an oral tablet that contains a fixed-dose combination of 600 mg of efavirenz, 200 mg of emtricitabine, and 300 mg of tenofovir disoproxil fumarate.

Your doctor will determine the appropriate dose and treatment duration based on your individual needs and condition.

Usage:

Atripla is a prescription medicine used to treat Human Immunodeficiency Virus (HIV) infection in adults and children who weigh at least 40 kg. HIV is the virus that causes Acquired Immune Deficiency Syndrome (AIDS). Atripla is a complete HIV treatment and should not be taken with other HIV medications. It contains three different antiretroviral drugs combined in one tablet: efavirenz, emtricitabine, and tenofovir disoproxil fumarate. Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that works by interfering with an enzyme called reverse transcriptase, which HIV needs to multiply. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) that also interferes with reverse transcriptase. Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor (NtRTI) that also interferes with reverse transcriptase. By blocking these enzymes, Atripla helps to lower the amount of HIV in the blood (viral load) and increase the number of immune cells (CD4+ T cells). This can help to improve the immune system and reduce the risk of HIV-related illnesses.

Mechanism of Action:
Atripla is a fixed-dose combination tablet containing three antiretroviral agents with different mechanisms of action against HIV-1:
• Efavirenz: A non-nucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1. It binds to HIV-1 reverse transcriptase (RT) non-competitively and inhibits RNA-dependent and DNA-dependent DNA polymerase activities.
• Emtricitabine: A nucleoside analogue of cytidine. It is phosphorylated by cellular enzymes to form emtricitabine 5'-triphosphate, which inhibits HIV reverse transcriptase by competing with the natural substrate deoxycytidine 5'-triphosphate and by being incorporated into newly forming viral DNA, resulting in chain termination.
• Tenofovir disoproxil fumarate: A nucleotide analogue reverse transcriptase inhibitor. It is converted in vivo to tenofovir, a nucleotide analogue of adenosine 5'-monophosphate. Cellular enzymes phosphorylate Tenofovir to the active metabolite tenofovir diphosphate, which inhibits HIV reverse transcriptase by direct competition with the natural substrate deoxyadenosine 5'-triphosphate and by DNA chain termination following its incorporation into viral DNA.

It is important to continue taking Atripla every day as prescribed to control your HIV infection. Follow the instructions in the patient information leaflet that comes with your medicine. It is essential to consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Atripla, discussing all possible aspects with your doctor or pharmacist is essential.

Side Effects:

The information below is a partial list of side effects; individual reactions can vary. Before starting Atripla, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common side effects: These are examples of some common side effects of Atripla, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning or if you experience any other concerning symptoms.
• Anxiety
• Diarrhea
• Difficulty concentrating
• Difficulty sleeping
• Dizziness
• Fatigue
• Headache
• Nausea
• Rash
• Unusual dreams
• Vomiting

Serious or rare side effects: Stop taking Atripla and seek immediate medical attention if you experience any of the following:
• Allergic reactions, including rash, hives, itching, swelling of the face, lips, tongue, or throat, and difficulty breathing
• Changes in mood or behaviour, including severe depression, severe sadness, anxiety, agitation, strange thoughts, or thoughts of suicide or self-harm
• Changes in skin colour
• Fast or irregular heartbeat, QT prolongation
• Fever
• Hallucinations
• Hepatitis B exacerbation in patients with existing HBV infection
• Psychosis or paranoia
• Signs of kidney problems, such as changes in the amount or colour of urine, swelling in the legs or ankles
• Signs of liver problems, such as yellowing of the skin or eyes (jaundice), dark urine, pale stools, loss of appetite, or pain in the upper right abdomen
• Symptoms of lactic acidosis, such as unusual tiredness or weakness, unusual muscle pain, stomach pain with nausea and vomiting, feeling cold, dizziness, or fast or irregular heartbeat
• Signs of pancreatitis, such as severe abdominal pain, nausea, vomiting, fever, and a fast heart rate
• Severe skin reactions, including blistering, peeling, or a rash covering a large area of the body
• Tingling, numbness, or pain in the hands or feet (peripheral neuropathy)

Contraindications:

This is not an exhaustive list of contraindications. It is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist before starting Atripla.

Atripla should not be used if:
• You are allergic to efavirenz, emtricitabine, tenofovir disoproxil fumarate, or any of the other ingredients in Atripla.
• You are currently taking certain other medications that can interact with Atripla and increase the risk of serious side effects (refer to the Drug Interactions section).

Tell your doctor about all of your medical conditions, past and present, before starting Atripla. This is crucial because certain conditions can affect whether Atripla is right for you. These conditions may include, but are not limited to:
• Bone problems or a history of fractures
• Depression or other mental health conditions
• Diabetes
• Heart problems, including changes in heart rhythm (QT prolongation)
• Hepatitis B virus (HBV) infection (your doctor will monitor you closely for worsening of hepatitis after stopping Atripla)
• Kidney problems
• Liver problems
• Seizures or a history of seizures
• Substance abuse (including alcohol or drug use)

Drug Interactions:

Before taking Atripla, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the highlights of prescribing information | Gilead Sciences, https://www.gilead.com/-/media/files/pdfs/medicines/hiv/atripla/atripla_pi.pdf

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Atripla can interact with many other medicines, and some interactions can be serious. Do not take Atripla with other emtricitabine or tenofovir disoproxil fumarate products, such as Emtriva, Viread, or Truvada. Other significant interactions include, but are not limited to:
• Anesthetics (e.g., Propofol, Ketamine)
• Antacids
• Antiretrovirals (e.g., Efavirenz, Nevirapine)
• Antidepressants (e.g., Bupropion)
• Certain antibiotics (e.g., clarithromycin)
• Certain antifungals (e.g., ketoconazole, itraconazole, voriconazole)
• Certain anticonvulsants (e.g., carbamazepine, phenytoin, phenobarbital)
• Certain medications for heart rhythm problems (antiarrhythmics)
• Chemotherapeutic Agents (e.g., Cyclophosphamide, Ifosfamide)
• Ergot derivatives (used for migraine headaches)
• H2-receptor antagonists (e.g., cimetidine, ranitidine
• Herbal products containing St. John's Wort
• Hormonal contraceptives (may be less effective when taken with Atripla)
• Methadone
• Opioids (e.g., Pethidine, Methadone)
• Other non-nucleoside reverse transcriptase inhibitors (NNRTIs)
• Protease inhibitors (other HIV medications)
• Proton pump inhibitors (PPIs) (e.g., omeprazole)
• Rifampin (used to treat tuberculosis)
• Sedatives and hypnotics (e.g., midazolam, triazolam)
• Warfarin

Pregnancy and Breastfeeding:

Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking Atripla. Efavirenz, one of the components of Atripla, can cause birth defects. Women should avoid becoming pregnant while taking Atripla and for 12 weeks after stopping it. You should use effective contraception during treatment and for 12 weeks after discontinuation. Breastfeeding is not recommended for women with HIV because of the risk of passing HIV to the baby through breast milk.

Use in Children:

Atripla's safety and effectiveness have been established in children weighing at least 40 kg who are able to swallow the tablet. It is not recommended for children weighing less than 40 kg.

Frequently Asked Questions about Atripla at CanadaPharmacyOnline.com:

Why is Atripla more affordable in Canada than in the United States?

Prescription drug prices, including Atripla, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

Can I buy over the counter from you?

No, Atripla requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

How long does it take for Atripla to work?

Atripla starts working to reduce the amount of HIV in your blood soon after you start taking it. However, seeing the full benefits may take some time, such as an increase in your CD4+ cell count. It is important to take Atripla consistently as prescribed by your doctor.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

Is there a limit on how many tablets I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Atripla at once, per your doctor's prescription.

What should I do if I miss a dose?

If you miss a dose of Atripla, take it as soon as you remember unless it is almost time for your next dose. If it is close to your next scheduled dose, skip the missed dose and take your next dose at the regular time. Do not take a double dose to make up for a missed one. It is important to take Atripla every day to effectively control your HIV infection.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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