Biktarvy (Bictegrav/Emtricit/Tenofov Alafenamide Hemifumarate)

Name: Biktarvy
Brand: Gilead Sciences
SKU: 7550
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Biktarvy Tablet

Manufacturer: Gilead Sciences

Country: Canada

Dosage: 50 mg/200 mg/25 mg

Qty-Price (USD):

Generic Equivalent of Biktarvy

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Bictegrav/Emtricit/Tenofov Alafenamide Hemifumarate Tablet

Manufacturer: Generic

Country: India

Dosage: 50 mg/200 mg/25 mg

Qty-Price (USD):

Biktarvy Information

Biktarvy at CanadaPharmacyOnline.com

The medication Biktarvy is sold under the brand name Biktarvy in various regions. In Canada, it's available as a brand-name product, Biktarvy, manufactured by Gilead Sciences. The specific manufacturer of your dispensed medication may vary.

Generic bictegrav/emtricit/tenofov alafenamide hemifumarate are sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Dosage

Brand Biktarvy is available as an oral tablet. It is available as a fixed-dose combination containing bictegravir 50 mg, emtricitabine 200 mg, and tenofovir alafenamide 25 mg.

Your doctor will determine the appropriate dose based on your individual needs and medical history.

Usage

Biktarvy is a prescription medication used for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 14 kg, with specific dosing dependent on weight. It is a complete regimen for the treatment of HIV-1 infection in treatment-naïve adults and pediatric patients weighing at least 14 kg, or to replace the current antiretroviral regimen in virologically suppressed adults and pediatric patients weighing at least 14 kg who are on a stable antiretroviral regimen with no history of treatment failure and no known substitutions associated with resistance to the individual components of Biktarvy.

Mechanism of Action
Biktarvy combines three antiretroviral agents with distinct mechanisms of action:
• Bictegravir (BIC): An integrase strand transfer inhibitor (INSTI). Bictegravir inhibits HIV-1 integrase, an enzyme essential for viral replication. Integrase is responsible for inserting viral DNA into the host cell's DNA. By blocking this process, bictegravir prevents the HIV-1 virus from replicating.
• Emtricitabine (FTC): A nucleoside reverse transcriptase inhibitor (NRTI). Emtricitabine is a synthetic nucleoside analog that is phosphorylated to its active triphosphate form. Emtricitabine triphosphate inhibits HIV-1 reverse transcriptase by competing with the natural substrate deoxycytidine-5'-triphosphate and by being incorporated into viral DNA, leading to chain termination.
• Tenofovir Alafenamide (TAF): A prodrug of tenofovir, which is also a nucleoside reverse transcriptase inhibitor (NRTI). Tenofovir alafenamide is an orally bioavailable phosphonamidate prodrug of tenofovir disoproxil fumarate. Tenofovir is phosphorylated to the active metabolite tenofovir diphosphate, which inhibits HIV-1 reverse transcriptase by competing with deoxyadenosine-5'-triphosphate and by terminating DNA chain elongation. TAF delivers tenofovir to HIV-1 target cells more efficiently than tenofovir disoproxil fumarate (TDF), resulting in lower plasma tenofovir concentrations and potentially a more favourable safety profile, particularly regarding kidney and bone health.

Always take Biktarvy exactly as your doctor prescribes, following the instructions in the product monograph in Canada. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Biktarvy, it's crucial to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects

The information below is a partial list of side effects; individual reactions can vary. Before starting Biktarvy, it's crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common Side Effects - The following are some common side effects of Biktarvy; other side effects may also occur. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Abnormal dreams
• Diarrhea
• Dizziness
• Fatigue
• Headache
• Insomnia
• Nausea
• Rash

Serious Side Effects - These are rare but potentially severe side effects. Seek immediate medical attention or call emergency services if you experience any of the following:
• Allergic reactions: Severe rash, hives, swelling of the face, lips, tongue, or throat, difficulty breathing, wheezing, and itching.
• Depression or mood changes: Including severe depression, anxiety, or thoughts of self-harm.v • Immune Reconstitution Inflammatory Syndrome (IRIS): In some patients with advanced HIV infection who start antiretroviral therapy, signs and symptoms of inflammation from previous opportunistic infections may arise shortly after beginning treatment.
• Kidney problems: New or worsening kidney problems, including kidney failure. Symptoms may include changes in urination, swelling in your legs or feet, or unusual tiredness. Your doctor will monitor your kidney function.
• Lactic acidosis and severe hepatomegaly with steatosis: This is a rare but serious condition that can be life-threatening. Symptoms include weakness, unusual muscle pain, trouble breathing, stomach pain with nausea and vomiting, feeling cold, dizziness, or an irregular heartbeat.
• Liver problems: Including hepatitis. Symptoms may include yellowing of the skin or eyes (jaundice), dark urine, light-coloured stools, loss of appetite, or pain on the right side below the ribs.
• New or worsening bone problems: Including bone pain, softening, or thinning of bones.
• Worsening of Hepatitis B (HBV) Infection: If you have both HIV-1 and HBV and stop taking Biktarvy, your HBV may suddenly worsen, potentially leading to liver failure. All patients should be tested for HBV before initiating Biktarvy. Do not stop Biktarvy without first talking to your healthcare provider, as your liver function will need to be monitored.

Contraindications

The following is not an exhaustive list of contraindications. Before starting Biktarvy, it's crucial to discuss all your medical conditions, past and present, and all medications you're taking with your doctor or pharmacist.

Biktarvy should not be used if:
• You are allergic to bictegravir, emtricitabine, tenofovir alafenamide, or any other ingredient in Biktarvy.
• You are taking dofetilide (an antiarrhythmic medication) due to the potential for serious and/or life-threatening adverse reactions.
• You are taking rifampin (an antibiotic) due to significantly decreased concentrations of bictegravir, which may result in a loss of therapeutic effect and the development of resistance.

Tell your doctor about all of your medical conditions, past and present, before starting Biktarvy. This is crucial because certain conditions affect whether Biktarvy is right for you. These conditions may include, but aren't limited to:
• Any unusual or allergic reaction to bictegravir, emtricitabine, tenofovir alafenamide, or other medications
• Bone problems
• History of depression or mental health issues
• Kidney problems (current or history of)
• Liver disease (current or history of, including hepatitis B or C)
• If you are co-infected with the hepatitis B virus (HBV). All patients should be tested for HBV before initiating Biktarvy. Discontinuation of Biktarvy in HBV co-infected patients may lead to severe acute exacerbations of hepatitis.

Drug Interactions

Before taking Biktarvy, it's essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the official product monograph | Gilead Sciences.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. It's also essential to inform your doctor about any herbal teas, recreational drugs, or significant dietary changes you're making, as these could potentially interact with Biktarvy. Biktarvy may interact with other medicines, but is not limited to:
• Antacids containing aluminum or magnesium: These can decrease the absorption of bictegravir. Biktarvy should be taken at least 2 hours before or 6 hours after taking antacids.
• Certain anticonvulsants (e.g., carbamazepine, oxcarbazepine, phenobarbital, phenytoin): May significantly decrease bictegravir concentrations. Co-administration is not recommended.
• Certain herbal supplements, Such as St. John's Wort, can significantly decrease bictegravir concentrations. Co-administration is not recommended.
• Certain other antiretrovirals: Including other drugs containing bictegravir, emtricitabine, or tenofovir, or specific other integrase inhibitors or NRTIs. Avoid co-administration.
• Dofetilide: Concomitant use is contraindicated.
• Metformin: Co-administration with Biktarvy may increase metformin concentrations.
• Rifabutin, Rifampin, Rifapentine: Rifampin is contraindicated. Rifabutin and rifapentine may significantly decrease bictegravir concentrations. Co-administration is not recommended.
• Supplements containing polyvalent cations (e.g., iron or calcium supplements) can decrease the absorption of bictegravir. Biktarvy should be taken at least 2 hours before or 6 hours after taking these supplements, or taken with food simultaneously.

Pregnancy and Breastfeeding

Biktarvy should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. The Antiretroviral Pregnancy Registry has been established to monitor pregnancy outcomes in women exposed to antiretroviral medications. Consult your doctor if you're pregnant or planning to become pregnant. The components of Biktarvy have been detected in human milk. Due to the potential for HIV transmission and the potential for severe adverse reactions in breastfed infants, mothers infected with HIV-1 should not breastfeed their infants. Consult your doctor for personalized advice.

Use in the Elderly

No overall differences in safety or effectiveness have been observed between elderly and younger patients. No dose adjustment of Biktarvy is typically required for elderly patients. However, caution should be exercised when administering Biktarvy to elderly patients, given the increased frequency of decreased hepatic, renal, or cardiac function, as well as concomitant disease or other drug therapies. Close monitoring is advisable.

Use in Children

Biktarvy is approved for use in pediatric patients weighing at least 14 kg. The strength of Biktarvy prescribed will depend on the child's weight: the 30 mg/120 mg/15 mg strength is for patients weighing 14 kg to less than 25 kg, and the 50 mg/200 mg/25 mg strength is for patients weighing at least 25 kg. The safety and effectiveness in pediatric patients weighing less than 14 kg have not been established. Dosage adjustments are based on weight.

Frequently Asked Questions about Biktarvy at Canada Pharmacy Online

Why is Biktarvy more affordable in Canada than in the United States?

Prescription drug prices, including Biktarvy, are generally lower in Canada than in the US. This is due to various factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, often resulting in lower costs compared to the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to providing you with the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on the number of tablets I can order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Biktarvy at a time, as per your doctor's prescription.

Can I buy over the counter from you?

No, Biktarvy requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

What is the best time to take Biktarvy?

Biktarvy is typically taken once daily with or without food. It's essential to take it consistently at the same time each day. Follow your doctor's specific instructions.

If I had hepatitis B in the past, will taking Biktarvy increase my chance of having it return?

Yes. If you have ever had hepatitis B, the virus can become active or get worse in the months after stopping Biktarvy. You’ll want to have frequent liver function tests while using this medication and for several months after your last dose.

Can I take antacids while on Biktarvy?

Certain antacids, laxatives, or buffered medicines can decrease Biktarvy’s effectiveness when taken at the same time. Take your dose on an empty stomach 2 hours before you take any other medicines, including antacids.

Can I get lactic acidosis while on Biktarvy?

While rare, it can happen that Biktarvy causes lactic acidosis (too much lactic acid). If you notice symptoms of weakness, tiredness, unusual muscle pain, shortness of breath, fast breathing, stomach pain, nausea, vomiting, cold or blue hands and feet, dizziness, or fast/abnormal heartbeats, consult your doctor right away.

Blog Post

STD-Related Mobile Apps Are On The Rise

Latest News

New injection for easier prevention of HIV infection in the EU and worldwide (article published on July 25, 2025)

Similar Drugs in the category of AIDS Medications, HIV Treatments:

Atripla Combivir Epivir Reyataz Norvir

The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

Reviews From Real Customers