DDAVP (Desmopressin)

Name: DDAVP
Brand: Ferring
SKU: 0319
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: DDAVP

Manufacturer: Ferring

Country: India

Dosage: 0.2 mg

Qty-Price (USD):

Type:

Product: DDAVP Tablet

Manufacturer: Ferring

Country: India

Dosage: 0.2 mg

Qty-Price (USD):

Type:

Product: DDAVP Nasal Spray (ON BACKORDER)

Manufacturer: Ferring

Country: India

Dosage: 10 mcg/2.5 ml

Qty-Price (USD):

Type:

Product: DDAVP Melt (Rapid Dissolve)

Manufacturer: Ferring

Country: Canada

Dosage: 60 mcg

Qty-Price (USD):

Type:

Product: DDAVP Melt (Rapid Dissolve)

Manufacturer: Ferring

Country: Canada

Dosage: 120 mcg

Qty-Price (USD):

Type:

Product: DDAVP Melt (Rapid Dissolve)

Manufacturer: Ferring

Country: Canada

Dosage: 240 mcg

Qty-Price (USD):

Generic Equivalent of DDAVP

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Desmopressin Tablet

Manufacturer: Generic

Country: Canada

Dosage: 0.1 mg

Qty-Price (USD):

Type:

Product: Desmopressin Tablet

Manufacturer: Generic

Country: Canada

Dosage: 0.2 mg

Qty-Price (USD):

DDAVP Information

medically reviewed by Dr. Bolanle Aina, Pharmacist on February 6, 2026.

DDAVP and Desmopressin at CanadaPharmacyOnline.com

The manufacturer of DDAVP (desmopressin) is Ferring Pharmaceuticals. This research-driven biopharmaceutical company originally developed this synthetic analogue of the natural antidiuretic hormone. In Canada, brand-name DDAVP is marketed by Ferring Inc. and is available in various delivery methods, including oral tablets, sublingual melts, and nasal sprays.

While the brand-name remains a leading option, generic desmopressin is produced by several global manufacturers that adhere to Health Canada's rigorous safety and bioequivalence standards. Common generic producers include Teva Canada and Apotex. Generic desmopressin is sourced from manufacturers that meet applicable regulatory standards, ensuring the medication provides the same clinical performance as the brand-name version. The specific manufacturer of your dispensed medication may vary based on pharmacy inventory.

Important Information about Generic Desmopressin

Generic desmopressin contains the same active ingredient as brand-name DDAVP. It must meet the same effectiveness and quality standards. This means it is designed to work in the same way as DDAVP. Studies have shown that generic desmopressin is bioequivalent to brand-name DDAVP, meaning it has similar absorption and achieves comparable blood concentrations. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage:

DDAVP (desmopressin) is available in several strengths and delivery formats to suit different medical needs:
• Oral Tablets: Available in 0.1 mg and 0.2 mg strengths.
• DDAVP Melt (Sublingual Tablets): Available in 60 mcg, 120 mcg, and 240 mcg. These dissolve instantly under the tongue without the need for water.
• Nasal Spray: Typically delivered as a metered dose of 10 mcg per spray. Available in 25 and 50 doses.

Your doctor will determine the appropriate dose and form based on your individual needs and medical conditions.

Usage:

DDAVP is primarily used to control the amount of urine the kidneys produce, mimicking the body's natural antidiuretic hormone (vasopressin). It is a standard treatment for central diabetes insipidus. In this condition, the body does not produce enough vasopressin, leading to extreme thirst and excessive urination. Additionally, DDAVP oral tablets and melts are frequently prescribed for Primary Nocturnal Enuresis (bedwetting) in children and adults, helping to reduce the volume of urine produced overnight so the bladder can hold it until morning. The nasal spray is not for bedwetting. Beyond fluid management, certain forms of DDAVP are used to treat mild to moderate Hemophilia A and von Willebrand's Disease. In these cases, the medication helps the body release stored clotting factors into the blood, preventing or stopping bleeding during surgery or after an injury.

Mechanism of Action
Desmopressin works as a highly selective agonist of the V2 receptors located in the collecting ducts of the kidneys. Under normal conditions, these receptors signal the kidneys to reabsorb water back into the bloodstream rather than excreting it as urine. By binding to these receptors, DDAVP increases the permeability of the kidney ducts to water, effectively concentrating the urine and reducing its total volume. This antidiuretic effect typically begins within an hour and lasts for 7 to 9 hours. Strict fluid restriction is mandatory. For bedwetting, fluid intake must be limited to a minimum from 1 hour before the dose until 8 hours after. Failure to do so can lead to water intoxication, a life-threatening condition.

In its role for bleeding disorders, DDAVP acts on the endothelial cells lining the blood vessels. It triggers the release of von Willebrand factor (vWF) and Coagulation Factor VIII from their storage sites (Weibel-Palade bodies). By temporarily boosting plasma levels of these essential proteins, the medication improves the blood's ability to form clots and significantly reduces the risk of prolonged bleeding.

Take DDAVP exactly as your doctor prescribes, following the instructions in the product monograph. Consult your doctor for personalized guidance and safe use. If you are taking it for bedwetting, it is usually taken 1 hour before bedtime. You must strictly limit your fluid intake from 1 hour before the dose until 8 hours after to prevent severe electrolyte imbalances.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting DDAVP, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of DDAVP (desmopressin). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of DDAVP; others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Flushing
• Headache
• Nasal congestion (spray form)
• Nausea

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Anaphylaxis: Severe allergic reaction involving swelling of the face or throat and difficulty breathing.
• Hyponatremia (Low Blood Sodium): Symptoms include severe headache, confusion, nausea, vomiting, unusual tiredness, or muscle weakness.
• Seizures: Often a result of severe water intoxication or low sodium.
• Thrombotic Events: Though rare, signs of blood clots, such as sudden chest pain or shortness of breath.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting DDAVP, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take DDAVP/desmopressin if:
• Heart Failure: Any condition in which fluid retention can be dangerous.
• Hyponatremia: You have a history of low blood sodium levels.
• Moderate to Severe Kidney Disease: Your kidneys cannot correctly process the medication or regulate fluid balance.
• Type IIB von Willebrand Disease: Using DDAVP in this specific subtype can cause a dangerous drop in platelet counts.

Tell your doctor about all of your medical conditions, past and present, before starting DDAVP. This is crucial as certain conditions affect the drug's safety.
• Cystic Fibrosis: These patients are more prone to hyponatremia.
• Fluid Imbalance: Tell your doctor if you have a fever, an infection, or stomach flu, as you may need to temporarily stop DDAVP.
• Polydipsia: Habitual or psychogenic excessive thirst.

Drug Interactions:

Before taking DDAVP, discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the package leaflet at https://assets.hpra.ie/products/Human/23791/DDAVPNasalDropsPIL-2163562-29092015115412-635791244542910000.pdf.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with DDAVP. DDAVP may interact with other medicines, including but not limited to:
• Antidepressants (SSRIs or Tricyclics): These can increase the risk of low sodium.
• Carbamazepine or Lamotrigine: These may increase the antidiuretic effect.
• Diuretics: Water pills can complicate DDAVP's fluid-regulating effects.
• NSAIDs: Such as ibuprofen or naproxen, which can increase the risk of water intoxication.

Pregnancy and Breastfeeding:

DDAVP has been used during pregnancy without evidence of harm to the fetus. However, it should be used only if the potential benefit outweighs the risk. It is not known if desmopressin passes into breast milk in significant amounts. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Use in Children:

DDAVP is approved for children (typically aged 6 and older for bedwetting). Careful fluid restriction is mandatory in pediatric patients to prevent water intoxication and seizures.

Frequently Asked Questions about DDAVP at Canada Pharmacy Online

Why is DDAVP more affordable in Canada than in the United States?

Prescription drug prices, including DDAVP, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many DDAVP I can order at once?

CanadaPharmacyOnline.com can dispense up to a three-month supply of DDAVP per prescription from your doctor.

Can I buy DDAVP over the counter from you?

No, DDAVP requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for DDAVP?

Yes, there is a generic alternative to DDAVP: Desmopressin.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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