Imdur (Isosorbide Mononitrate)

Name: Imdur
Brand: AstraZeneca
SKU: 1519
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Imdur

Manufacturer: AstraZeneca

Country: India

Dosage: 30 mg

Qty-Price (USD):

Generic Equivalent of Imdur

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Isosorbide Mononitrate

Manufacturer: Generic

Country: Canada

Dosage: 60 mg

Qty-Price (USD):

Imdur Information

Imdur and Isosorbide mononitrate at CanadaPharmacyOnline.com

The manufacturer of Imdur (isosorbide mononitrate) varies globally as the brand-name version has transitioned through different corporate ownerships and regional licensing agreements. Initially developed by AstraZeneca, the brand rights in many markets have been sold to specialized pharmaceutical firms. In Canada, the brand-name Imdur is currently manufactured and marketed by Juno Pharmaceuticals Corp. In international markets, such as the United Kingdom and Australia, the brand may be associated with AstraZeneca or Clinect Pty Ltd.

Generic isosorbide mononitrate is sourced from manufacturers that meet applicable regulatory standards. Common generic producers include Apotex, Teva, and Intas Pharmaceuticals. The specific manufacturers of your dispensed medication may vary.

Important Information about Generic Isosorbide Mononitrate

Generic isosorbide mononitrate contains the same active ingredient as brand-name Imdur. It must meet the same effectiveness and quality standards. This means it is designed to work in the same way as Imdur. Studies have shown that generic isosorbide mononitrate is bioequivalent to brand-name Imdur, meaning it has similar absorption and achieves comparable blood concentrations. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage:

Imdur (isosorbide mononitrate) is available in the strength of 30 mg oral tablets.

Generic isosorbide mononitrate is available in 60 mg oral tablets.

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

Imdur (isosorbide mononitrate) is a long-acting nitrate primarily used to prevent angina pectoris caused by coronary artery disease. Angina is a condition that presents with severe pain in the chest, often also spreading to the shoulders, arms, and neck, primarily due to insufficient blood supply to the heart. It is important to note that Imdur will not work fast enough to treat an acute angina attack that has already started. For immediate relief of a sudden attack, use a fast-acting nitrate, such as sublingual nitroglycerin.

Mechanism of Action
Imdur is an organic nitrate and the major active metabolite of isosorbide dinitrate. It acts as a vasodilator by releasing nitric oxide, which relaxes the smooth muscles in the blood vessel walls.

By widening the veins, Imdur reduces the amount of blood returning to the heart, which lowers the heart's workload and oxygen demand. It also dilates the coronary arteries, improving blood flow to the heart muscle itself. This approach helps maintain a balance between oxygen supply and demand, preventing the onset of chest pain during daily activities.

Unlike many other blood pressure medications, nitrates lose their effectiveness if they are in the bloodstream 24 hours a day. To prevent this tolerance, Imdur is specifically designed to be taken once daily (usually in the morning) to provide a 7-to-10-hour nitrate-free period overnight. Taking it too frequently will make the drug stop working.

Take Imdur exactly as your doctor prescribes, following the instructions in the product monograph. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Imdur, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Imdur (isosorbide mononitrate). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Imdur; others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Dizziness or lightheadedness, particularly when standing up quickly
• Flushing
• Headache

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Anaphylaxis: Severe allergic reaction involving swelling of the face or throat and difficulty breathing.
• Methemoglobinemia: Bluish-colored lips, fingernails, or palms (an extremely rare blood-oxygen condition).
• Paradoxical angina: An increase in chest pain shortly after taking the medication.
• Severe hypotension: Fainting, extreme weakness, or a racing heartbeat.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Imdur, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Imdur/isosorbide mononitrate if:
• Allergies: You have a known hypersensitivity to nitrates or nitrites.
• PDE5 inhibitors: You are taking medications for erectile dysfunction, such as Sildenafil (Viagra), Tadalafil (Cialis), or Vardenafil (Levitra). This combination can cause a life-threatening drop in blood pressure.
• Severe conditions: You have severe anemia, increased intracranial pressure, or are in a state of circulatory collapse or shock.

Tell your doctor about all of your medical conditions, past and present, before starting Imdur. This is crucial as certain conditions affect the drug's safety.
• Kidney or liver disease: While generally safe, your doctor will monitor your condition as these organs process and clear the medication.
• Low blood pressure: Imdur can worsen hypotension, especially in those who are volume-depleted.
• Recent heart attack: Avoid Imdur in the early phase of an acute myocardial infarction if there is a risk of right ventricular infarction

Drug Interactions:

Before taking Imdur, discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the patient information leaflet at https://assets.hpra.ie/products/Human/32333/2109968.PPA1151_027_001.dc554918-0a80-4b41-bf7d-10ed60d175b5.000001ProductLeafletApproved.130507.pdf.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Imdur. Imdur may interact with other medicines, including but not limited to:
• Calcium Channel Blockers: May lead to symptomatic orthostatic hypotension.
• Other Vasodilators: Alcohol and other blood pressure medications can amplify the blood-pressure-lowering effects of Imdur, leading to severe dizziness or fainting.
• Riociguat is strictly contraindicated for use with nitrates.

Pregnancy and Breastfeeding:

The safety of Imdur during pregnancy has not been fully established. It should be used only if the potential benefit justifies the potential risk to the fetus. Limited data suggest that isosorbide mononitrate may pass into breast milk. Inform your doctor if you are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed.

Use in Children:

The safety and effectiveness of Imdur in pediatric patients have not been established. Use in children is not recommended without specific specialist guidance.

Frequently Asked Questions about Imdur at Canada Pharmacy Online

Why is Imdur more affordable in Canada than in the United States?

Prescription drug prices, including Imdur, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Imdur I can order at once?

CanadaPharmacyOnline.com can dispense up to a three-month supply of Imdur per prescription from your doctor.

Can I buy Imdur over the counter from you?

No, Imdur requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Imdur?

Yes, there is a generic alternative to Imdur: Isosorbide mononitrate.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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