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Omnaris (Ciclesonide)

Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
Type: drug type
Product: Omnaris Nasal Spray
Manufacturer: Takeda
Country: Australia
Dosage: 50 mcg/120 dose
Qty-Price (USD):
Type: drug type
Product: Omnaris Nasal Spray
Manufacturer: Covis Pharma
Country: Canada
Dosage: 50 mcg/120 dose
Qty-Price (USD):

Generic Equivalent of Omnaris
Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
There is no generic product of Omnaris.

Omnaris Information

portrait medically reviewed by Dr. HaVy Ngo, Pharmacist on June 18, 2025.

Omnaris at CanadaPharmacyOnline.com

Brand Omnaris is manufactured by Covis Pharma in Canada. It is also available in Australia.

The generic version of ciclesonide is currently unavailable (at this pharmacy).

Dosage:

Omnaris is a nasal spray; each actuation (spray) provides 50 mcg of the active ingredient, ciclesonide. Each bottle contains approximately 120 metered actuations.

Usage:

Omnaris (ciclesonide) is a prescription nasal spray primarily used to treat nasal symptoms associated with allergic rhinitis. Allergic rhinitis, commonly known as hay fever, can occur seasonally or perennially (year-round due to triggers like dust mites or pet dander). For more information, refer to the Consumer Medicine Information | NPS MedicineWise https://www.nps.org.au/assets/medicines/d74f08be-a728-4c63-ab5e-a53300ff6613.pdf

Mechanism of Action:
Omnaris belongs to a class of drugs known as corticosteroids. It works by reducing inflammation in your nose to help with allergy symptoms such as stuffiness, congestion, itching, and sneezing. When you spray Omnaris, its active ingredient, ciclesonide, quickly changes into a more active form inside your nasal lining. This activated form then works to "turn down" the body's inflammatory response by decreasing the release of chemicals that cause swelling, itching, and mucus production. It also helps shrink the tiny blood vessels in your nose, easing congestion and redness. By calming this inflammation, Omnaris relieves a stuffy, runny, or itchy nose and sneezing caused by allergies.

Use Omnaris exactly as your doctor prescribes. Do not change your dosage or stop using the medication without consulting your doctor. Follow the instructions in the product monograph in Canada: https://pdf.hres.ca/dpd_pm/00059998.PDF. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Omnaris, it is essential to discuss all possible aspects with your doctor or pharmacist.

Side Effects:

Below is a partial list of side effects; individual reactions can vary. Before starting Omnaris, it is crucial to discuss potential side effects and risks with your doctor or pharmacist.

Common side effects: These are examples of some common side effects of Omnaris, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Cold-like symptoms (e.g., nasopharyngitis)
• Ear pain
• Headache
• Nasal discomfort
• Nasal irritation: Burning, stinging, or dryness in the nose.
• Nosebleeds (epistaxis): This is one of the most frequently reported side effects with nasal corticosteroids.
• Sore throat
• Stuffy nose or nasal congestion (sometimes, paradoxically, if the spray itself irritates)
• Taste changes

Serious or rare side effects: Stop taking Omnaris and seek immediate medical attention if you experience any of the following:
• Adrenal gland problems (Adrenal suppression): Although rare with proper use, especially in children or with very high doses over a long time, the body's natural production of steroids can be affected. Symptoms might include extreme tiredness, muscle weakness, dizziness, or weight loss.
• Allergic reactions: Hives, rash, itching, swelling of the face, lips, tongue, or throat, or difficulty breathing (seek immediate medical attention).
• Eye problems: Cataracts (clouding of the eye lens), glaucoma (increased pressure in the eye), blurred vision, eye pain, or other vision changes. (More likely with long-term use; regular eye exams may be recommended.)
• Fungal infection in the nose or throat (Thrush): White patches in the nose or mouth.
• Impaired wound healing: If you have had recent nasal surgery, injury, or ulcers, Omnaris should generally not be used until healing is complete, as steroids can slow this process.
• Nasal septal perforation: A hole in the cartilage that separates the nostrils. While rare with Omnaris, nasal corticosteroids are a known risk, especially if sprayed directly onto the septum.
• Nasal sores or ulcers: Crusting or sores inside the nose.
• Signs of infection: Corticosteroids can sometimes mask signs of disease or make you more prone to infections. Report fever, chills, severe sore throat, pain or swelling, or unusual discharge.
• Slowed growth in children and adolescents: Long-term use of nasal corticosteroids in children and adolescents may, in rare cases, affect their growth velocity. Doctors usually monitor the growth of children during long-term treatment.

Contraindications:

This is not an exhaustive list of contraindications. It is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist before starting Omnaris.

Omnaris should not be used if:
• Known Hypersensitivity/Allergy: You should not use Omnaris if you have a known allergy to ciclesonide or any other ingredient in the Omnaris formulation. Allergic reactions can be severe, including hives, swelling of the face, lips, or throat, and difficulty breathing.
• Nasal Septal Perforation: If you have a pre-existing hole in the cartilage separating your nostrils (nasal septum), using a nasal corticosteroid like Omnaris might worsen it.
• Recent Nasal Surgery, Trauma, or Unhealed Sores/Ulcers in the Nose: Corticosteroids can slow wound healing. Therefore, Omnaris should not be used if you have recently had nasal surgery, a nasal injury, or have unhealed sores or ulcers inside your nose, until healing has occurred.
• Untreated Infections in the Nose or Throat: Omnaris, like other corticosteroids, can suppress the immune system. Therefore, it should not be used if you have an active, untreated infection (viral, bacterial, fungal, or parasitic) in your nose or throat. Using it in such cases could worsen the infection or allow it to spread. Specific examples include:
o Chickenpox or Measles: If you haven't had these diseases, been vaccinated against them, or been exposed, using a corticosteroid like Omnaris can make these infections more serious or even fatal.
o Ocular herpes simplex (herpes infection of the eye).
o Tuberculosis (active or quiescent) of the respiratory tract.
o Untreated local or systemic bacterial, fungal, or parasitic infections.

Tell your doctor about all your medical conditions, past and present, before starting Omnaris. This is crucial because certain conditions can also lead to further contraindications. These conditions may include, but are not limited to:
• Glaucoma or Cataracts: If you have a history of or are at risk for these eye conditions, Omnaris should be used cautiously and under close medical monitoring, as nasal corticosteroids can potentially worsen them over long-term use.
• Immunosuppressed Patients: Individuals whose immune systems are suppressed for any reason (e.g., due to other medications) are more susceptible to infections and should use Omnaris cautiously and under strict medical supervision.
• Systemic Corticosteroid Withdrawal: If you are transitioning from systemic (oral or injected) corticosteroids to Omnaris, your doctor must carefully monitor you for signs of adrenal insufficiency or corticosteroid withdrawal symptoms.

Drug Interactions:

Before taking Omnaris, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the Australia product monograph | Chiesi: https://www.chiesi.com.au/omnaris_PI.pdf

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Omnaris may interact with other medicines such as:
• Additive Steroid Effects: While less of a direct "interaction," if you are already using other corticosteroids (e.g., an oral steroid, an asthma inhaler containing a steroid, or another steroid nasal spray), using Omnaris adds to your total steroid burden. Your doctor will consider all steroid exposure to minimize overall risk.
• Increased Risk of Systemic Side Effects: If Omnaris is used with a strong CYP3A4 inhibitor, the amount of steroid absorbed into your bloodstream might increase. This could lead to side effects associated with systemic corticosteroids, such as adrenal gland suppression (where your body's natural steroid production is lowered), increased blood sugar, or, rarely, Cushing's syndrome symptoms.
• Strong CYP3A4 Inhibitors:
o Ketoconazole: This is a prominent example often cited. Ketoconazole (an antifungal medication, particularly the oral form) can significantly increase the levels of ciclesonide in the body.
o Ritonavir and Cobicistat: These are antiviral medications often used to treat HIV. They are very strong CYP3A4 inhibitors and can also increase systemic exposure to ciclesonide.
o Other strong CYP3A4 inhibitors (e.g., some other antifungals, certain antibiotics, specific grapefruit juice components in huge amounts) could theoretically have a similar effect, though the risk with a nasal spray is generally lower than with oral steroids.

Pregnancy and Breastfeeding:

If you are pregnant, planning to become pregnant, or breastfeeding, it's essential to talk with your doctor before using Omnaris. Omnaris is a nasal spray, and while only a small amount usually gets into your bloodstream, animal studies with similar medications have shown potential risks to an unborn baby. For breastfeeding, it's not fully known how much of the medication passes into breast milk. However, most experts consider nasal corticosteroids generally acceptable during breastfeeding due to the very low amount likely to reach the baby. Discuss the potential risks and benefits with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Use in Children:

Omnaris is generally not recommended for children younger than 6 years of age for seasonal allergic rhinitis, and under 12 for perennial allergic rhinitis, as its safety and effectiveness have not been established in these younger age groups, and there's a higher risk of systemic side effects, including potential effects on growth. Always consult your child’s doctor for the most appropriate and safest treatment.

Frequently Asked Questions about Omnaris at CanadaPharmacyOnline.com

Why is Omnaris more affordable in Canada than in the United States?

Prescription drug prices, including Omnaris, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs than the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Can I buy over the counter from you?

No, Omnaris requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on getting you the lowest prices on high-quality products.

Can I buy Omnaris Nasal Spray over the counter from you?

No, Omnaris Nasal Spray requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

Is there a generic for Omnaris Nasal Spray?

No, there is no generic alternative for this product.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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Prescriptions Dispensed from Canada are Dispensed by Candrug Pharmacy #18985. 202A 8322-130th Street, Surrey, British Columbia, Canada V3W 8J9, 604-543-8711. Pharmacy Manager: Carol Hou.
This pharmacy is duly licensed in the province of British Columbia, Canada by the College of Pharmacists of BC. If you have any questions or concerns you can contact the college at: 200-1765 West 8th Ave Vancouver, BC V6J 5C6 Canada.
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