Rupall (Rupatadine Fumarate)

Name: Rupall
Brand: Pediapharm
SKU: 7343
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Rupall Oral Solution

Manufacturer: Pediapharm

Country: Canada

Dosage: 1 mg/ml/120 ml

Qty-Price (USD):

Type:

Product: Rupall Tablet

Manufacturer: Pediapharm

Country: Canada

Dosage: 10 mg

Qty-Price (USD):

Generic Equivalent of Rupall

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Rupatadine Fumarate Tablet

Manufacturer: Generic

Country: Canada

Dosage: 10 mg

Qty-Price (USD):

Type:

Product: Rupatadine Fumarate Tablet

Manufacturer: Generic

Country: India

Dosage: 10 mg

Qty-Price (USD):

Rupall Information

medically reviewed by Carol Hou (BSc. Pharm) on December 8, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Rupall and Rupatadine Fumarate at CanadaPharmacyOnline.com

The brand Rupall (rupatadine) is marketed in Canada by Pediapharm, a division of Medexus Pharmaceuticals.

Generic rupatadine fumarate is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturers of your dispensed medication may vary.

Important Information about Generic Rupatadine Fumarate

Generic rupatadine fumarate contains the same active ingredient as brand-name Rupall and must meet the same effectiveness and quality standards. This means it is designed to work in the same way as Rupall. Studies have shown that generic rupatadine fumarate is bioequivalent to brand-name Rupall, meaning it has similar absorption and achieves comparable blood concentrations. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information about generic drug approval and bioequivalence, you can visit the FDA website: https://www.fda.gov/drugs/generic-drugs/generic-drug-facts.

Dosage:

The brand-name Rupall is available in:
• Oral Solution in 1 mg/ml/ in a 120 ml bottle
• Tablets in 10 mg

The generic rupatadine fumarate is available as 10 mg oral tablet.

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

Rupall (rupatadine fumarate) is a prescription-strength, non-sedating medication taken once daily to effectively manage symptoms of common allergic conditions. Its main uses include treating Allergic Rhinitis—reducing symptoms such as sneezing, a runny nose, and itchy, watery eyes—and Chronic Spontaneous Urticaria (hives), helping to lessen itching and the appearance of wheals.

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Mechanism of Action:
Rupall (rupatadine) works through a dual mechanism to effectively fight allergy symptoms. It primarily acts as a highly selective antihistamine, blocking histamine's effects at H1 receptors. This is important for quickly relieving immediate symptoms such as sneezing, itching, and hives. Additionally, Rupall uniquely acts as a Platelet-Activating Factor (PAF) antagonist. PAF is another potent inflammatory mediator released during allergic reactions, which can lead to ongoing swelling and congestion. By blocking both histamine and PAF, Rupall provides a more comprehensive and powerful anti-allergy effect, targeting both the immediate allergic response and the underlying inflammation.

Take Rupall exactly as your doctor prescribes, following the instructions in the product monograph in Canada. Consult a doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Rupall, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Rupall (rupatadine fumarate). It is not an exhaustive list, and individual reactions can vary.

Common side effects – These are common side effects of Rupall, but others are possible. Contact your doctor promptly if any side effects persist, worsen, or are concerning, or if you experience any other concerning symptoms.
• Dizziness
• Dry mouth
• Fatigue
• Headache
• Sleepiness (Somnolence)
• Weakness (Asthenia)

Other Potential Side Effects (less common):
• Abdominal pain
• Back pain
• Constipation
• Cough
• Diarrhea
• Dry throat
• Indigestion (Dyspepsia)
• Irritability
• Nausea
• Nosebleed (Epistaxis)
• Rhinitis (Nasal inflammation)
• Sore throat
• Thirst
• Vomiting

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Abnormal heart rhythm (including fast, slow, or pounding heartbeat, severe dizziness, or fainting, particularly due to QT prolongation risk)
• Allergic reaction (signs may include rash, itching, swelling of the face, lips, tongue, or throat, or trouble breathing)
• Muscle damage (rarely reported signs include unexplained muscle pain, tenderness, or weakness, or brown/discolored urine)

Contraindications:

The following are key contraindications and important warnings (not an exhaustive list). Before starting Rupall, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do NOT take Rupall (rupatadine fumarate) if:
• Hypersensitivity: You have a known allergy or hypersensitivity to rupatadine or to any of the inactive ingredients in the tablet or oral solution formulation.

Tell your doctor about all of your medical conditions, past and present, before starting Rupall. This is crucial as certain conditions affect the drug's safety.
• Cardiac Arrhythmias (Rupall may increase the risk of QT interval prolongation, which can affect heart rhythm, especially in susceptible individuals.)
• Hypokalemia or Hypomagnesemia (Electrolyte imbalances that can increase the risk of heart rhythm problems).
• Known QT Prolongation (A pre-existing heart condition that increases the risk of abnormal heart rhythms.)
• Known Risk Factors for QT Prolongation (This includes clinically significant bradycardia (slow heart rate), acute myocardial ischemia, or a family history of sudden cardiac death.)

Drug Interactions:

Before taking Rupall, discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the product package leaflet at https://www.medicines.org.uk/emc/files/pil.2501.pdf.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Rupall. Rupall may interact with other medicines, but is not limited to:

Significant Interactions (Require Caution or Avoidance)
• Antifungal Medications: Ketoconazole
• Macrolide Antibiotics: Erythromycin
• Protease Inhibitors (used for HIV/AIDS): Ritonavir

Moderate Interactions (Use with Caution)
• Central Nervous System (CNS) Depressants: Rupall, while generally considered non-sedating, may enhance the effects of other CNS depressants.
o Alcohol (may increase the risk of drowsiness and impaired performance)
o Sedatives or Tranquilizers
• Other CYP3A4 Inhibitors: Other moderate inhibitors of the CYP3A4 enzyme can also increase Rupall concentration.

Food/Beverage Interaction
Grapefruit and grapefruit juice should be avoided while taking Rupall, as they are potent CYP3A4 inhibitors that can significantly increase Rupall levels in the bloodstream, increasing the risk of side effects.

Interactions Affecting the Heart
• Antiarrhythmics (e.g., Amiodarone, Quinidine)
• Certain Antidepressants (e.g., Citalopram, Escitalopram)
• Certain Antipsychotics (e.g., Haloperidol)

Pregnancy and Breastfeeding:

The safety of Rupall (rupatadine) during pregnancy and breastfeeding is not well-established because there aren't enough studies in pregnant or nursing women to confirm its effects on a baby. While animal studies showed no direct harm to the fetus at relevant doses, the lack of human data means Rupall is generally recommended only if the healthcare provider determines that the benefits far outweigh any potential unknown risks to the developing fetus or nursing infant. Therefore, women who are pregnant, planning to get pregnant, or breastfeeding should consult their healthcare provider to discuss the risks and consider potentially safer, well-studied alternatives for managing their allergies.

Use in Children:

Rupall (rupatadine) is safe for use in children, but its use is carefully limited by age and formulation. It is approved for kids aged 2 years and older, provided they receive the correct, weight-based dose with the oral solution. For teenagers aged 12 and older, the standard 10 mg tablet is usually prescribed. However, Rupall is not recommended for children under 2 years because its safety and effectiveness haven't been established in that very young group. When used according to the specified age and weight guidelines, it is an effective option for treating allergic rhinitis and chronic hives in children.

Frequently Asked Questions about Rupall at CanadaPharmacyOnline:

Why is Rupall more affordable in Canada than in the United States?

Prescription drug prices, including Rupall, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on offering you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Rupall tablets I can order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Rupall at one time, as per your doctor's prescription.

Can I buy Rupall over the counter from you?

No, Rupall requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Rupall?

Yes, there is a generic alternative for this product, called rupatadine fumarate.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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