Oruvail (Ketoprofen Extended Release)

Name: Oruvail
Brand: Brand
SKU: 5593
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Oruvail Capsule

Manufacturer: Brand

Country: New Zealand

Dosage: 200 mg

Qty-Price (USD):

Generic Equivalent of Oruvail

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Ketoprofen Extended Release Enteric Coated Tablet

Manufacturer: Generic

Country: Canada

Dosage: 50 mg

Qty-Price (USD):

Type:

Product: Ketoprofen Extended Release Enteric Coated Tablet

Manufacturer: Generic

Country: Canada

Dosage: 100 mg

Qty-Price (USD):

Type:

Product: Ketoprofen Extended Release Sustained Release Tablet

Manufacturer: Generic

Country: Canada

Dosage: 200 mg

Qty-Price (USD):

Oruvail Information

Oruvail and Ketoprofen extended release at CanadaPharmacyOnline.com

The original manufacturer of brand-name Oruvail (ketoprofen extended-release) is Sanofi-Aventis. In October 2025, Sanofi announced the discontinuation of Oruvail SR 200 mg capsules worldwide. As of early 2026, remaining stocks are being depleted, and the brand is being delisted from many international pharmaceutical schedules.

The generic ketoprofen extended release is produced by several reputable manufacturers that meet the strict standards of Health Canada and the FDA. Common generic producers include Viatris (formerly Mylan), Teva, and Apotex. The specific manufacturer of the medication dispensed may vary based on pharmacy inventory. Generic ketoprofen extended release is sourced from manufacturers that meet applicable regulatory standards.

Important Information about Generic Ketoprofen Extended Release

Generic ketoprofen extended release contains the same active ingredient as brand-name Oruvail. It must meet the same effectiveness and quality standards. This means it is designed to work like Oruvail. Studies have shown that generic ketoprofen extended release is bioequivalent to brand-name Oruvail, meaning it has similar absorption and achieves comparable blood concentrations. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca.

Dosage:

Oruvail (ketoprofen extended release) is available in the following oral strengths:
• Capsule: 200 mg
• Tablet: 50 mg, 100 mg, and 200 mg

The standard adult dosage is 200 mg taken once daily. Because it is an extended-release formula, it provides steady pain relief for 24 hours. It is not recommended for acute pain that requires a fast-acting response.

Usage:

Oruvail is used to manage the pain, swelling, and stiffness associated with rheumatoid arthritis and osteoarthritis. It is also used to treat other types of joint and muscle pain, such as ankylosing spondylitis (spinal arthritis) and acute gout. As a long-acting treatment, it is intended to help patients maintain mobility and comfort during daily activities.

Mechanism of Action
Ketoprofen extended release is a non-steroidal anti-inflammatory drug (NSAID). When your body is injured or dealing with chronic arthritis, it produces natural chemicals called prostaglandins. These chemicals are responsible for the pain you feel and the visible swelling in your joints. Ketoprofen blocks the enzymes COX-1 and COX-2, which produce prostaglandins that cause pain and inflammation. By lowering the levels of these chemicals in your body, the medication calms the redness and heat in your joints. It significantly dulls the pain signals sent to your brain.

Take Oruvail exactly as your doctor prescribes, as directed in the product monograph. Take the medicine at the same time each day. It must be taken with food and a full glass of water to protect your stomach. The capsules must be swallowed whole. Do not crush, chew, or open them, as this will destroy the extended-release mechanism and could cause a dangerous dose to be released all at once.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Oruvail, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Oruvail (ketoprofen extended release). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Oruvail; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Dizziness
• Drowsiness
• Gas
• Headache
• Indigestion, heartburn, or mild stomach pain
• Nausea

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Cardiovascular Events: Chest pain, shortness of breath, or sudden weakness on one side of the body.
• Kidney Issues: Swelling of the feet or ankles, or a change in the amount of urine.
• Liver Problems: Yellowing of the eyes or skin (jaundice).
• Severe Skin Reactions: A widespread rash with blisters and peeling.
• Stomach Bleeding: Black, tarry stools, or vomiting that looks like coffee grounds.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Oruvail, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Oruvail/ketoprofen extended release if:
• Active Ulcers: Do not use Oruvail if you have an active stomach ulcer or intestinal bleeding.
• Allergies: You have a known hypersensitivity to ketoprofen extended release
• Recent Heart Surgery: Do not use immediately before or after heart bypass surgery (CABG).

Tell your doctor about all of your medical conditions, past and present, before starting Oruvail. This is crucial as certain conditions affect the drug's safety.
• Aspirin-Sensitive Asthma: If you have ever had an asthma attack or severe allergic reaction to aspirin or other NSAIDs.
• Kidney Disease: Severe renal impairment may make this drug unsafe.

Drug Interactions:

Before taking Oruvail, discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the consumer medicine information at https://www.medsafe.govt.nz/consumers/cmi/o/Oruvail-sr.pdf.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, herbal supplements, recreational drugs, and any significant dietary changes, as these may interact with Oruvail. Oruvail may interact with other medicines, including but not limited to:
• Blood Pressure Meds: It may make ACE inhibitors and diuretics less effective.
• Blood Thinners: Like warfarin or aspirin, which can significantly increase the risk of stomach bleeding.
• Lithium: Oruvail can increase the levels of lithium in your blood to dangerous levels.
• Methotrexate: Can increase the toxicity of this medication if taken together.

Pregnancy and Breastfeeding:

Inform your doctor if you are pregnant or planning to become pregnant. Oruvail should not be taken after 20 weeks of pregnancy, as it can cause serious heart and kidney problems in the unborn baby. It may also lead to complications during labor. Consult your doctor to weigh the benefits and risks of this medicine before using it while nursing. Ketoprofen passes into breast milk in very small amounts. However, it is considered low risk.

Use in Children:

Oruvail is not approved for use in children under 18 years of age. Its safety and effectiveness in children have not been established.

Frequently Asked Questions about Oruvail at Canada Pharmacy Online

Why is Oruvail more affordable in Canada than in the United States?

Prescription drug prices, including Oruvail, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how many Oruvail I can order at once?

CanadaPharmacyOnline.com can dispense up to a three-month supply of Oruvail per prescription from your doctor.

Can I buy Oruvail from you over the counter?

No, Oruvail requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Oruvail?

Yes, the generic alternative, ketoprofen extended release, is available.

Blog Post:

Is There a Connection Between Pregnancy & Rheumatoid Arthritis?

Latest News:

Updated EULAR recommendations guide treatment decisions for rheumatoid arthritis (news published on March 13, 2026)

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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