Clarinex (Desloratadine/Aerius)

Name: Clarinex
Brand: Bayer
SKU: 2325
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Clarinex Oral Syrup Bubble Gum Flavour

Manufacturer: Bayer

Country: Canada

Dosage: 0.5 mg/ml (100ml)

Qty-Price (USD):

Type:

Product: Clarinex

Manufacturer: Bayer

Country: Canada

Dosage: 5 mg

Qty-Price (USD):

Generic Equivalent of Clarinex

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Desloratadine/Aerius

Manufacturer: Generic

Country: India

Dosage: 5 mg

Qty-Price (USD):

Clarinex Information

medically reviewed by Dr. HaVy Ngo, Pharmacist on December 23, 2025.

Clarinex and Desloratadine/Aerius at CanadaPharmacyOnline.com

Clarinex (desloratadine/aerius) is manufactured and marketed by Organon, which was spun off from Merck & Co. (known as MSD outside the U.S. and Canada) in 2021.

It is also known as Aerius in Canada, Europe, and many other countries. While in the United States, it is marketed under the name Clarinex. Generic desloratadine/aerius is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturers of your dispensed medication may vary.

It is available in the United States, Canada, and many other countries worldwide.

Important Information about Generic Desloratadine/Aerius

Generic desloratadine/aerius contains the same active ingredient as brand-name Clarinex and must meet the same effectiveness and quality standards. This means it is designed to work in the same way as Clarinex. Studies have shown that generic desloratadine/aerius is bioequivalent to brand-name Clarinex, meaning it has similar absorption and achieves comparable blood concentrations. However, individual responses to medication can vary due to factors such as metabolism, genetics, and other health conditions.

For more information about generic drug approval and bioequivalence, please visit the FDA website: https://www.fda.gov/drugs/buying-using-medicine-safely/generic-drugs.

Dosage:

At this pharmacy, Aerius and its generic equivalent are available in 5 mg tablet strength.

It is also available as a bubble-gum-flavored oral syrup at a strength of 0.5 mg/mL in a 100 mL bottle.

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

Clarinex (desloratadine/aerius) is a long-acting, non-sedating antihistamine that provides 24-hour relief from common allergy symptomsf. It is also approved for the treatment of chronic idiopathic urticaria (chronic hives), helping to reduce pruritus and the appearance of welts in both adults and children.

Mechanism of Action:
Clarinex is a second-generation antihistamine that acts as a potent H1-receptor inverse agonist. Rather than just "blocking" or competing with histamine, it binds to the H1 receptors and actively keeps them in an "inactive" state.

When you encounter a trigger such as pollen, your body releases histamine. Clarinex prevents this chemical from binding to its receptors, thereby reducing symptoms such as sneezing and itching. Because the medication has a high affinity for peripheral receptors and does not readily cross the blood-brain barrier, it provides relief with a much lower risk of sleepiness compared to older, first-generation antihistamines.

Take Clarinex exactly as your doctor prescribes, following the instructions in the product monograph in Canada. Consult a doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before starting Clarinex, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects of Clarinex (desloratadine/aerius). It is not an exhaustive list, and individual reactions can vary.

Common side effects: These are common side effects of Clarinex; other side effects are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Dizziness
• Dry mouth
• Fatigue
• Pharyngitis (sore throat)
• Somnolence (drowsiness)

Other Potential Side Effects (less common):
• Dysmenorrhea (painful menstruation)
• Dyspepsia (indigestion)
• Muscle pain
• Nausea

Serious Side Effects: Seek immediate medical attention or call emergency services if you experience any of the following symptoms:
• Anaphylaxis: Severe allergic reaction (swelling of the lips/tongue, hives, or difficulty breathing).
• Liver Issues: Symptoms like yellowing of the skin or eyes (jaundice), dark urine, or severe right-sided abdominal pain. (This correlates with the liver enzyme/bilirubin elevations mentioned in your draft)
• Tachycardia: A racing, pounding, or irregular heartbeat.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Clarinex, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Do not take Clarinex/desloratadine/aerius if:
• Allergies: You have a known allergy to desloratadine or loratadine (Claritin), as they are chemically related.
• Inactive Ingredients: You are allergic to specific fillers, such as lactose (found in some tablet versions) or dye.

Tell your doctor about all of your medical conditions, past and present, before starting Clarinex. This is crucial as certain conditions affect the drug’s safety.
• Kidney Disease: Because the kidneys help clear the drug, patients with poor renal function often need an adjusted dosing schedule (such as 5 mg every other day).
• Liver Problems: If the liver isn't processing the medication efficiently, a doctor may need to change how often you take it.
• Phenylketonuria (PKU): This is important if you use the RediTabs (dissolvable tablets), as they contain phenylalanine (aspartame).

Drug Interactions:

Before taking Clarinex, discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the patient information from Organon at https://www.organon.com/product/usa/pi_circulars/c/clarinex/clarinex_ppi.pdf.

Provide your doctor with a complete list of all your medications, including prescription, over-the-counter (OTC), vitamins, and herbal supplements, as these may interact with Clarinex.

While several medications can increase the levels of desloratadine in your system, clinical trials have shown that these increases are generally not associated with a higher risk of side effects. These medications include:
• Antibiotics: Such as erythromycin or azithromycin.
• Antifungals: Such as ketoconazole.
• Heartburn Medications: Such as cimetidine.
• Antidepressants: Such as fluoxetine.

Although these interactions have been noted in studies, Clarinex is generally considered to have a very high safety margin, even when blood levels rise slightly.

Pregnancy and Breastfeeding:

The safety of Clarinex (desloratadine/Aerius) during pregnancy is not fully established; it should be used only if the potential benefit outweighs the risk to the fetus. While animal studies have not shown significant fetal harm, there are no adequate and well-controlled studies in pregnant women. For breastfeeding women, desloratadine is excreted in human milk. This may cause side effects in the nursing infant, such as irritability or drowsiness, and may also reduce milk production. It is essential to consult a healthcare provider to determine whether to continue the medication or breastfeeding.

Use in Children:

Clarinex is FDA-approved for children as young as 6 months old when using the oral solution (syrup). It is approved for the treatment of perennial (year-round) allergic rhinitis and chronic hives in infants aged 6 months and older, and for seasonal allergies in children aged 2 years and older. The RediTab (orally disintegrating tablet) is available for children 6 years and older. Because it is a non-sedating antihistamine, it provides effective relief with a much lower risk of causing sleepiness than older, first-generation antihistamines.

Frequently Asked Questions about Clarinex at Canada Pharmacy Online

Why is Clarinex more affordable in Canada than in the United States?

Prescription drug prices, including Clarinex, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to offering you the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Is there a limit on how much Clarinex I can order at one time?

CanadaPharmacyOnline.com can dispense up to a three-month supply of Clarinex per your doctor's prescription.

Can I buy Clarinex over the counter from you?

In the U.S., Clarinex is prescription-only. You cannot buy it over the counter (OTC). In many other countries, including Canada and much of Europe, Aerius is available over the counter without a prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Clarinex?

Yes, there is a generic alternative for this product, called desloratadine/aerius.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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