Delstrigo (Dorvirine/Lamivudine/Tenofovir)

Name: Delstrigo
Brand: Merck
SKU: 7538
Availability: InStock

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Qty-Price (USD)

Type:

Product: Delstrigo (CURRENTLY UNAVAILABLE)

Manufacturer: Merck

Country: Canada

Dosage: 100 mg/300 mg/300 mg

Qty-Price (USD):

Generic Equivalent of Delstrigo

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There is no generic product of Delstrigo.

Delstrigo Information

Delstrigo at CanadaPharmacyOnline.com

Brand Delstrigo (doravirine/lamivudine/tenofovir) is manufactured by Merck in many countries worldwide, including Canada.

The generic doravirine/lamivudine/tenofovir is currently unavailable (at this pharmacy).

Dosage:

Delstrigo is commonly available as 100 mg/300 mg/300 mg oral tablets.

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

Delstrigo (doravirine/lamivudine/tenofovir) is a prescription medication primarily used to treat HIV-1 infection in adults and pediatric patients weighing at least 35 kg who have not received HIV treatment before, or are switching from another HIV regimen that is already controlling the virus. HIV attacks the immune system, weakening the body’s ability to fight infections. Delstrigo does not cure HIV, but when taken consistently, it lowers the amount of virus in the blood (viral load), helps protect the immune system, and reduces the risk of HIV-related illness and transmission.

Mechanism of Action:
Delstrigo (doravirine/lamivudine/tenofovir) is a combination of three antiretroviral medicines that block HIV replication in different ways. Doravirine blocks a viral enzyme HIV needs to make copies of itself, while lamivudine and tenofovir interfere with viral genetic material. By attacking the virus at multiple steps, Delstrigo helps keep HIV under control and prevents it from multiplying.

Take Delstrigo exactly as your doctor prescribes, following the instructions in the highlights of the prescribing information that accompany the medication. Consult your doctor for personalized guidance and safe use.

Side Effects:

The information below outlines potential side effects associated with Delstrigo (doravirine/lamivudine/tenofovir). It is not an exhaustive list, and individual reactions can vary. This information is for educational purposes and should not replace professional medical advice. Before starting Delstrigo, it is crucial to discuss possible side effects and risks with your doctor or pharmacist.

Common side effects - These are common side effects of Delstrigo; others are possible. Contact your doctor promptly if any side effects persist, worsen, or concern you, or if you experience any other concerning symptoms.
• Abnormal dreams and insomnia (trouble sleeping);
• Diarrhea;
• Dizziness;
• Fatigue;
• Headache;
• Nausea

Serious or rare side effects- Seek immediate medical attention or call emergency services if you experience any of the following: • Bone pain;
• Lactic Acidosis (a buildup of acid in the blood) and Severe Liver Problems (Hepatomegaly with steatosis);
• Reduced urination;
• Signs of an allergic reaction, such as swelling, breathing difficulties, swelling of the face, lips, or throat;
• Symptoms of liver problems, including yellowing of the skin or eyes, dark urine, and severe fatigue

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Delstrigo, it is essential to discuss all your medical conditions, past and present, as well as all medications you are currently taking, with your doctor or pharmacist.

Do not take Delstrigo if:
• You have a known allergy to doravirine/lamivudine/tenofovir or any of the ingredients in the medication.
• You are taking strong CYP3A inducers.

Tell your doctor about all of your medical conditions, past and present, before starting Delstrigo. This is crucial because certain conditions can affect whether Delstrigo is right for you. These conditions may include, but are not limited to:
• Kidney disease (Because Delstrigo is a fixed-dose combination, it should not be used by patients with an estimated creatinine clearance ($CrCl$) of less than 50 mL/min).
• Liver disease
• Osteoporosis or other bone problems

Drug Interactions:

Before taking Delstrigo, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the product monograph.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. It is also essential to inform your doctor about any herbal teas, recreational drugs, or significant dietary changes you are making, as these could potentially interact with Delstrigo. Delstrigo may interact with other medicines, but is not limited to:
• Certain seizure medications, such as carbamazepine, phenytoin, phenobarbital, and oxcarbazepine, can reduce doravirine levels and compromise HIV control.
. • Enzalutamide: This common prostate cancer medication is a strong CYP3A inducer and is specifically contraindicated (must not be used) with Delstrigo.
• Other HIV medications containing lamivudine or tenofovir can lead to overdose or increased side effects and should not be taken together.
• Nephrotoxic medications, such as high-dose NSAIDs, certain antivirals, or aminoglycoside antibiotics, may increase the risk of kidney damage when used with tenofovir.
• Rifampin, rifapentine, and rifabutin – These can significantly lower doravirine levels, making Delstrigo less effective and increasing the risk of HIV resistance. These medicines should generally not be used together.
• Sustained-Release (SR) medications: Use caution with medications that are also processed by the kidneys, as they may compete with the tenofovir in Delstrigo.
• St. John’s wort may lower doravirine levels and should not be used with Delstrigo.

Pregnancy and Breastfeeding:

Delstrigo may be used during pregnancy. However, your doctor will carefully assess the benefits and risks before prescribing it. If you are living with HIV, breastfeeding is not recommended, even if your viral load is well controlled. HIV can pass to a baby through breast milk, and the medications in Delstrigo can also be present in breast milk. If you are pregnant, breastfeeding, or planning to become pregnant, it is crucial to consult your doctor immediately.

HBV Exacerbation:

Before starting Delstrigo, you should be tested for the presence of chronic Hepatitis B virus (HBV) before or when initiating Delstrigo. Severe acute exacerbations of Hepatitis B have been reported in patients who are co-infected with HIV-1 and HBV and have discontinued lamivudine or tenofovir disoproxil fumarate, two of the components of Delstrigo.

Frequently Asked Questions about Delstrigo at Canada Pharmacy Online:

Why is Delstrigo more affordable in Canada than in the United States?

Prescription drug prices, including Delstrigo, are generally lower in Canada than in the U.S. due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to providing you with the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784. Visit our How to Order page for more information or to learn about the ordering process.

Is there a limit on the number of tablets I can order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Delstrigo at a time, as per your doctor's prescription.

Can I buy over the counter from you?

No, Delstrigo requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It typically takes 7-18 business days for your order to be delivered from our pharmacy.

Is Delstrigo a cure for HIV?

No. Delstrigo controls HIV but does not cure it. Consistent daily use is essential.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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