Dymista Nasal Spray (Azelastine/Fluticasone)

Name: Dymista Nasal Spray
Brand: Meda Pharms
SKU: 6883
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Dymista Nasal Spray

Manufacturer: Meda Pharms

Country: United Kingdom

Dosage: 137 mcg/50 mcg-120 dose

Qty-Price (USD):

Type:

Product: Dymista Nasal Spray

Manufacturer: Meda Pharms

Country: United Kingdom

Dosage: 137 mcg/50 mcg/120 dose

Qty-Price (USD):

Type:

Product: Dymista Nasal Spray

Manufacturer: BGP Pharma

Country: Canada

Dosage: 137 mcg/50 mcg/120 dose

Qty-Price (USD):

Generic Equivalent of Dymista Nasal Spray

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Azelastine/Fluticasone

Manufacturer: Generic

Country: Canada

Dosage: 137 mcg/50 mcg/120 dose

Qty-Price (USD):

Type:

Product: Azelastine/Fluticasone (Ezicas AZ - Intas)

Manufacturer: Generic

Country: India

Dosage: 140 mcg/50 mcg/70 dose

Qty-Price (USD):

Dymista Nasal Spray Information

medically reviewed by Carol Hou (BSc. Pharm) on June 11, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Dymista Nasal Spray and Azelastine/Fluticasone at CanadaPharmacyOnline.com

The Brand Dymista is manufactured by BGP Pharma Inc. and is available in Canada. It is also marketed by Meda Pharms in the United Kingdom.

Generic azelastine/fluticasone is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information Generic Azelastine/Fluticasone:

Generic azelastine/fluticasone suspension contains the same active ingredients as brand-name Dymista. It is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as Dymista. While bioequivalence studies are conducted to ensure generic medications have comparable absorption rates and overall effects, individual responses to any medication can vary. Talk to your doctor or pharmacist if you have questions about using generic azelastine/fluticasone.

For information about generic drug approval and bioequivalence, please visit Access to Generic Drugs in Canada | Canada.ca

Dosage:

Dymista (Azelastine/Fluticasone) is commonly sold at the strength of 137 mcg Azelastine / 50 mcg Fluticasone per spray, containing 120 doses per bottle. Generic versions of Azelastine/Fluticasone are also available. These may be offered in comparable strengths (e.g., 140 mcg Azelastine / 50 mcg Fluticasone per spray) and typically come in various dose counts, such as 70 or 120, depending on the specific manufacturer or the retailer's inventory from different generic suppliers.

Your doctor will determine the appropriate dose based on your needs and medical condition.

Usage:

Brand Dymista is a prescription medication used to treat nasal symptoms such as congestion, sneezing, and a runny nose caused by seasonal and perennial allergies. It also provides relief of hay fever and associated eye symptoms.

For more information, refer to the product labeling information: https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202236s000lbl.pdf

Mechanism of Action:
Dymista (azelastine/fluticasone) works in two key ways to tackle allergy symptoms effectively. First, it contains azelastine, an antihistamine that quickly blocks the effects of histamine, a natural substance your body releases during an allergic reaction. This helps rapidly relieve sneezing, itching, and a runny nose. Second, it includes fluticasone, a corticosteroid that reduces the inflammation and swelling in your nasal passages. This component helps to ease congestion and overall irritation, providing longer-lasting relief. Combining these two active ingredients, Dymista offers quick symptom control and addresses the underlying inflammation, providing comprehensive relief for your allergy symptoms.

Use Dymista exactly as your doctor prescribes. Do not change your dosage or stop using the medication without consulting your doctor and following the instructions in the package leaflet information | Electronic Medicine Compendium (eMC). Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before taking Dymista, it is essential to discuss all possible aspects with your doctor or pharmacist.

Side Effects:

Below is a partial list of side effects; individual reactions can vary. Before starting Dymista, discussing potential side effects and risks with your doctor or pharmacist is crucial.

Common side effects: These are examples of some common side effects of Dymista, but others are possible. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Drowsiness or dizziness: This is due to the antihistamine component (azelastine). It's important to be cautious when driving or operating machinery until you know how Dymista affects you, and to avoid alcohol or other sedating medications.
• Dry or sore throat, cough.
• Headache
• Nasal irritation: This might include mild stinging, burning, itching, or dryness inside the nose.
• Nosebleeds (epistaxis): This is the most frequently reported side effect and is usually minor.
• Unpleasant taste (dysgeusia) or smell can be due to the medication dripping into the throat, especially if you tilt your head too far. A drink of water after using the spray can help.

Serious or rare side effects: Stop taking Dymista and seek immediate medical attention if you experience any of the following:
• Adrenal suppression: Very high doses or prolonged use can, in rare cases, affect the body's natural hormone production.
• Delayed wound healing: If you have recent nasal surgery, injury, or ulcers, Dymista might delay healing. Your doctor may advise against use until healing is complete.
• Growth suppression in children: Long-term use of corticosteroids, even nasal sprays, can potentially affect growth. Your doctor will monitor your child's growth if they are on Dymista.
• Increased risk of infection: Fluticasone is a corticosteroid that can slightly suppress the immune system, potentially making people more susceptible to infections.
• Nasal septal perforation: This is a rare but serious side effect where a hole can form in the wall separating your nostrils.
• Signs of a serious allergic reaction: This is rare but can include hives, rash, severe itching, swelling of the face, lips, tongue, or throat, or difficulty breathing. Seek immediate medical help if these occur.
• Sores or white patches inside the nose or throat: This could indicate a localized infection (like a fungal infection, e.g., Candida albicans) or, rarely, damage to the nasal lining.
• Vision changes can include blurred vision, eye pain, or seeing halos around lights. Though rare, prolonged use of corticosteroids can contribute to glaucoma (increased pressure in the eye) or cataracts. Regular eye check-ups may be recommended, especially with long-term use.

Contraindications:

This is not an exhaustive list of contraindications. It is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist before starting Dymista.

Dymista should not be used if:
• Hypersensitivity/Allergy: You should not use Dymista if you have a known allergy or severe hypersensitivity reaction to either of its active ingredients (azelastine hydrochloride or fluticasone propionate) or any of the other inactive ingredients in the spray. An allergic reaction could include symptoms like rash, itching, swelling of the face/lips/tongue, or difficulty breathing (anaphylaxis)

Telling your doctor about all your medical conditions, past and present, before starting Dymista. This is crucial because certain conditions affect whether Dymista is right for you. These conditions may include, but are not limited to:
• Concomitant use of Ritonavir (or other strong CYP3A4 inhibitors): Ritonavir, an antiretroviral medication, can significantly increase the levels of fluticasone in the body, leading to systemic corticosteroid effects (like Cushing's syndrome or adrenal suppression). Co-administration is generally not recommended. Other strong CYP3A4 inhibitors like ketoconazole should also be used with caution.
• Exposure to Chickenpox or Measles: If you haven't had these infections or aren't vaccinated, using a corticosteroid like fluticasone can make you more susceptible to a severe or even fatal course of these diseases. Inform your doctor immediately if you are exposed to these viruses.
• Glaucoma or Cataracts: Corticosteroids, even nasal sprays, can potentially contribute to the development or worsening of glaucoma (increased pressure in the eye) and cataracts. If you have a history of these eye conditions or experience changes in vision, your doctor will monitor you closely.
• Recent Nasal Surgery, Trauma, or Sores/Ulcers in the Nose: Dymista contains a corticosteroid, which can impair wound healing. Therefore, it's generally advised to avoid using Dymista until your nose has fully healed from any recent surgery, injury, sores, or ulcers inside your nose.
• Severe Liver Disease: In patients with severe liver impairment, the body may not process fluticasone as efficiently, leading to higher levels of the medication in the body and potentially increased systemic side effects. Your doctor will assess the risk and benefit.
• Untreated Infections (Fungal, Bacterial, Viral, or Parasitic): Corticosteroids can suppress the immune system, potentially worsening existing infections, especially active tuberculosis, fungal infections (like Candida albicans in the nose), or ocular herpes simplex. If you have such an infection, your doctor must treat it appropriately before or while considering Dymista.

Drug Interactions:

Before taking Dymista, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the Dymista product monograph in Canada.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. Dymista may interact with other medicines such as:
• Central Nervous System (CNS) Depressants and Alcohol: Azelastine, the antihistamine component, can cause drowsiness and dizziness. When combined with other CNS depressants, these effects can be significantly amplified. Alcohol, sedatives, tranquilizers, sleeping pills, opioid pain medications, certain antidepressants (e.g., amitriptyline), and other antihistamines (especially older, more sedating ones like diphenhydramine). Increased sedation, dizziness, impaired judgment, thinking, and motor coordination. Avoid alcohol and use caution with other CNS depressants. Do not drive or operate machinery until you know how Dymista affects you.
• Cimetidine: Cimetidine (a medication used to reduce stomach acid) can inhibit the metabolism of azelastine, leading to increased plasma levels of azelastine. Increased levels of azelastine could potentially increase its side effects, particularly drowsiness. Use with caution; your doctor may monitor you.
• Corticosteroids: Using Dymista with other corticosteroid medications (e.g., oral steroids like prednisone, or other inhaled or nasal steroid sprays) can increase the overall systemic corticosteroid load. Increased risk of systemic corticosteroid side effects, including adrenal suppression. Your doctor will be aware of all corticosteroid medications you are using to manage your total exposure.
• Ketoconazole (an antifungal medication) is another potent CYP3A4 inhibitor. While the interaction may be less severe than with ritonavir, caution is advised, and your doctor may monitor you for increased corticosteroid side effects. Other strong CYP3A4 inhibitors (e.g., some macrolide antibiotics like erythromycin, certain protease inhibitors like atazanavir, clarithromycin). While erythromycin doesn't appear to significantly alter fluticasone levels when inhaled, caution is still warranted. Increased risk of systemic corticosteroid side effects, including adrenal suppression, Cushing's syndrome symptoms (e.g., weight gain, moon face, high blood pressure), increased blood sugar, osteoporosis, and cataracts. Inform your doctor if you are taking any of these medications. Your doctor may need to adjust your treatment or monitor you closely.
• Strong CYP3A4 Inhibitors: Fluticasone, the corticosteroid component, is primarily metabolized by an enzyme in the liver called cytochrome P450 3A4 (CYP3A4). Strong inhibitors of this enzyme can slow down the breakdown of fluticasone, leading to higher levels of fluticasone in the body and potentially increased systemic corticosteroid side effects. Ritonavir (an antiviral medication, especially for HIV): This is a very strong CYP3A4 inhibitor. Coadministration with Dymista is generally NOT recommended due to the significant increase in fluticasone levels and risk of serious systemic corticosteroid effects like Cushing's syndrome and adrenal suppression.

Pregnancy and Breastfeeding:

If you are pregnant, planning to become pregnant, or breastfeeding, it is crucial to speak with your doctor about Dymista. While there are no extensive studies on pregnant or breastfeeding women, the low systemic absorption of its ingredients when used as a nasal spray suggests a relatively low risk. Discuss the potential risks and benefits with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Use in Children:

Dymista nasal spray is generally not recommended for those under 6 years of age, as its safety and effectiveness haven't been established in this very young group. For children aged 6 to 11 years, Dymista may be prescribed, typically at the same dosage as adults (one spray in each nostril twice daily), particularly when simpler treatments haven't adequately controlled moderate to severe allergic rhinitis. However, because Dymista contains a corticosteroid, doctors will carefully consider its use. They may monitor a child's growth if used long-term, aiming for the lowest effective dose for the shortest duration necessary. For adolescents 12 years and older, Dymista is generally indicated and used as in adults. Always consult your child's doctor to determine if Dymista is appropriate for their specific allergy needs and to ensure proper usage and monitoring.

Frequently Asked Questions about Dymista at CanadaPharmacyOnline.com:

Why is Dymista more affordable in Canada than in the United States?

Prescription drug prices, including Dymista, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs than the US, where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How do I order from your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784; for more information or to learn about the ordering process, visit our How to Order page.

Can I buy over the counter from you?

No, Dymista requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Does Dymista cause drowsiness?

Dymista is an antihistamine nasal spray that may make you drowsy. Do not drive a vehicle or operate machinery if you are drowsy. Stop using this medication and call your doctor if you experience severe drowsiness.

Is there a generic for Dymista?

Yes, a generic alternative for this product is Azelastine/Fluticasone.

Blog Post:

How Does Air Pollution Affect Men’s Health?

News:

How to beat spring allergies: 5 top tips from pharmacy experts (article published on May 23, 2025)

Similar Drugs in the category of Allergy Medication:

Nasonex Nasal Spray Omnaris Rupall Beconase Hayfever Aq Nasal Spray Alrex

The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

Reviews From Real Customers