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Phenergan (Promethazine)

Qty-Price (USD)
Type: drug type
Product: Phenergan
Manufacturer: Pendopharm Pharmascience
Country: Canada
Dosage: 50 mg

Generic Equivalent of Phenergan
Qty-Price (USD)
Type: drug type
Product: Promethazine
Manufacturer: Generic
Country: India
Dosage: 10 mg
Type: drug type
Product: Promethazine
Manufacturer: Generic
Country: India
Dosage: 25 mg

Phenergan Information

reviewed by Dr. HaVy Ngo, Pharmacist on 1/2/2024 11:23:54 AM.

Phenergan Details (Brand and Generic) currently offers the brand Phenergan (Histantil) from Canada manufactured by Pendopharm Pharmascience. The generic Promethazine comes from India from another manufacturer. Our customers may also purchase other Allergy Medications such as EpiPen and Reactine. For more information and further assistance, please call Customer Service at 1866.920.3784.


The brand Phenergan is available in the strength of 50 mg tablets only. The generic Promethazine is available in the strength of 10 mg and 25 mg tablets.


Phenergan (Promethazine) is a prescription medication used to treat the symptoms of allergic conditions, including nausea, vomiting, motion sickness, pre-and post-operative sedation, and obstetric sedation. It is also used to treat short-term sleep problems (insomnia), including when a cough, cold or itching keeps you awake at night. The active ingredient in Phenergan is promethazine hydrochloride. Promethazine belongs to a group of medicines called phenothiazines. It works by blocking a natural substance (histamine) that your body makes during an allergic reaction. It also works directly on the brain to help you feel more relaxed. Promethazine helps control symptoms but will not treat the cause of the symptoms or the underlying diseases.

Side Effects and Precautions

Stop using the medication and get medical care if you have an allergic reaction. Signs of an allergic reaction may include difficulty breathing, hives (rash on your body), swelling of your face, lips, tongue, or throat—If you experience any of these symptoms, please call 911 or seek emergency medical care at the nearest emergency room (ER).

The common side effects of Phenergan are drowsiness, headaches, nightmares and feeling dizzy, restless or confused.

Stop using Phenergan and contact your doctor right away if you have any of the serious side effects such as:
• Being more sensitive to the sun than usual;
• Blurred vision;
• Difficulty in passing urine;
• Dry mouth;
• Feeling tired or sleepy, tiredness, disorientation, having nightmares, headaches;
• Feeling restless;
• Feeling dizzy, lightheaded, faint (hypotension);
• Feeling confused, especially in older people;
• Loss of appetite (anorexia), indigestion;
• Unpleasant sensation or an overwhelming urge to move the legs (also called Restless Legs Syndrome)

The above information is a summary and may not contain all the side effect information. If you still have questions about side effects, you should talk to your doctor or pharmacist so they can address all your concerns.

Warnings and Interactions

Before using Phenergan, inform your doctor or pharmacist if you are allergic to promethazine hydrochloride or any other ingredients in Phenergan products. The signs of an allergic reaction include a rash, swallowing or breathing problems, and swelling of your lips, face, throat or tongue. Phenergan contains lactose. You should not take this drug if you have hereditary lactose intolerance or total lactase deficiency. Do not drink alcohol while taking Promethazine. Alcohol can worsen Phenergan’s drowsiness and sleepiness. Additionally, you should avoid medications that can make you even more drowsy; examples are alcohol, marijuana (cannabis), opioid pain medicines, anxiety and sleep medications, treatment for seizures and muscle relaxer. Avoid driving, operating machinery, or performing any tasks that requires alertness until you know how your body reacts to this medication. To help you sleep, take Promethazine 20 minutes before bed. It usually takes about 30 minutes to work. To prevent motion sickness, take Promethazine the night before a long journey or 1 to 2 hours before a short journey. Talk to your doctor if there is no improvement in your condition or if it worsens.

You may feel tired or sleepy after taking this medicine or the morning after taking this medicine. If this happens, do not drive or use any tools or machines

Before you start using Phenergan, inform your doctor about your medical history, especially if you have:
• Epilepsy;
• Eye problems such as primary narrow-angle glaucoma;
• Hearing problems;
• Kidney problems;
• Liver problems;
• Problems peeing or emptying your bladder;
• Serious heart problems

Tell your doctor about all the medications you use, including prescriptions, over-the-counter medications, herbal products, and vitamin supplements. Tell your doctor if you are pregnant or plan to become pregnant. You should not take Phenergan if you are breastfeeding. This is because small amounts may pass into mothers' milk. This can be harmful to your baby. There may be a drug interaction between Phenergan and other drugs such as dopamine, disopyramide, cabergoline, methyldopa, metrizamide and pentamidine. Not all possible drug interactions are listed here. Talk to your doctor or pharmacist about any questions regarding drug interactions that you may have.

Questions and Answers

Why is Phenergan more affordable from Canada than the United States?

In general, all drug prices, not only Phenergan, are more affordable to order from Canada because the price of both the brand and generic medication is regulated by the government. Also, since we established in 2006, our vision is to provide safe and affordable medication to people in the US.

Is it safe to buy Phenergan from your pharmacy?

Our products are sourced only from facilities certified by authorities in the countries we import them from. has a rigorous process for selecting our partners, so that you, our customer, get the safest medicine. We are also a Certified Canadian Pharmacy that adheres to the requirements imposed by the Province of British Columbia.

How much does Phenergan tablets cost in Canada?

At our pharmacy, the cost of Phenergan 50 mg starts at $42.99 for 100 tablets.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on getting you the lowest prices on high-quality products.

How do I order from your pharmacy?

Ordering Phenergan from us is very simple. You can place the order online or call Customer Service at 1866.920.3784. For additional information or for the ordering process, visit our How to Order page.

Are your Phenergan prices competitive?

Yes, we are proud to offer some of the most competitive prices across Canadian pharmacies. In some cases, we might be able to either match or beat our competitors' prices. Please call our friendly customer service at 1866.920.3784.

Is there a limit on how many Phenergan I am allowed to order at one time? can only dispense a maximum of a three-month supply of Phenergan at one time, as per your doctor's prescription.

Can I buy Phenergan over the counter from you?

No, Phenergan requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Phenergan?

Yes, there is a generic alternative for this product called Promethazine.

Can this medication be used in children?

Phenergan should not be used in children under 2 years of age. Phenergan can cause severe breathing problems or death in very young children. Follow your doctor’s instructions exactly when giving this medication to a child of any age.

What should I avoid while taking this medication?

Phenergan can cause side effects that may impair your thinking or reactions. Avoid driving or operating heavy machinery until you know how this medication affects you. Avoid consuming alcohol, as it can increase some of the side effects of this medication.

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