Symtuza (Cobicistat/Darunavir/Emtricitabine/Tenofovir)

Name: Symtuza
Brand: Janssen-Cilag
SKU: 7572
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Symtuza (CURRENTLY UNAVAILABLE)

Manufacturer: Janssen-Cilag

Country: Canada

Dosage: 800 mg/150 mg/200 mg/10 mg

Qty-Price (USD):

Generic Equivalent of Symtuza

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

There is no generic product of Symtuza.

Symtuza Information

Symtuza at CanadaPharmacyOnline.com

Brand Symtuza (cobicistat/darunavir/emtricitabine/tenofovir) is manufactured by Janssen-Cilag in many countries worldwide, including Canada.

The generic cobicistat/darunavir/emtricitabine/tenofovir is currently unavailable (at this pharmacy).

Dosage:

Symtuza is commonly available as 800 mg/150 mg/200 mg/10 mg oral tablets.

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

Symtuza (cobicistat/darunavir/emtricitabine/tenofovir) is a prescription medication primarily used to treat HIV-1 infection in adults and certain adolescents. HIV is a virus that attacks the immune system, specifically CD4 cells, weakening the body's ability to fight infections. Antiretroviral therapy like Symtuza helps control the virus, improve immune function, and reduce the risk of HIV-related complications. Symtuza does not cure HIV, but consistent daily use helps keep the virus suppressed. Symtuza must be taken with a meal or snack. Taking it on an empty stomach significantly reduces the absorption of darunavir, which can lead to treatment failure and drug resistance.

Mechanism of Action:
Symtuza (cobicistat/darunavir/emtricitabine/tenofovir) combines four antiretroviral agents with complementary actions to block HIV replication at different stages of its life cycle. Darunavir inhibits the HIV protease enzyme, preventing the virus from maturing. Cobicistat boosts darunavir levels by slowing its breakdown in the body. Emtricitabine and tenofovir alafenamide block reverse transcriptase, an enzyme HIV needs to make copies of itself. By targeting multiple pathways, Symtuza lowers viral load and helps maintain immune health.

Take Symtuza exactly as your doctor prescribes, following the instructions on the drug website accompanying the medication. Consult your doctor for personalized guidance and safe use.

Side Effects:

The information below outlines potential side effects associated with Symtuza (cobicistat/darunavir/emtricitabine/tenofovir). It is not an exhaustive list, and individual reactions can vary. This information is for educational purposes and should not replace professional medical advice. Before starting Symtuza, it is crucial to discuss possible side effects and risks with your doctor or pharmacist.

Common side effects - These are common side effects of Symtuza; others are possible. Contact your doctor promptly if any side effects persist, worsen, or concern you, or if you experience any other concerning symptoms.
• Abdominal discomfort;
• Diarrhea;
• Fatigue;
• Headache;
• Mild rash;
• Nausea

Serious or rare side effects- Seek immediate medical attention or call emergency services if you experience any of the following:
• Severe skin reaction, including painful rash with blisters, peeling, or fever;
• Signs of an allergic reaction, such as swelling, breathing difficulties, swelling of the face, lips, or throat;
• Signs of kidney or liver problems;
• Signs of lactic acidosis, including unusual tiredness, fast breathing, or cold hands and feet;

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Symtuza, it is essential to discuss all your medical conditions, past and present, as well as all medications you are currently taking, with your doctor or pharmacist.

Do not take Symtuza if:
• You have a known allergy to cobicistat, darunavir, emtricitabine, tenofovir, or any of the ingredients in the medication.
• You have severe liver impairment.

Tell your doctor about all of your medical conditions, past and present, before starting Symtuza. This is crucial because certain conditions can affect whether Symtuza is right for you. These conditions may include, but are not limited to:
• A history of medication resistance
• Diabetes
• Kidney problems
• Liver conditions, such as hepatitis B or hepatitis C

Drug Interactions:

Before taking Symtuza, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, refer to the product monograph.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. It is also essential to inform your doctor about any herbal teas, recreational drugs, or significant dietary changes you are making, as these could potentially interact with Symtuza. Symtuza may interact with other medicines, but is not limited to:
• Heart rhythm medications – Some antiarrhythmics can reach dangerous levels, increasing the risk of serious heart rhythm problems.
• Seizure medications – Drugs such as carbamazepine or phenytoin may reduce Symtuza's effectiveness.
• Sedatives and sleep medications – may increase sedation or breathing problems when used with Symtuza.
• Rifampin and similar antibiotics can significantly reduce Symtuza levels. Using rifampin with Symtuza can cause the treatment to fail.
• Cholesterol-lowering medications may increase the risk of muscle injury.
• St. John's wort can reduce the effectiveness of antivirals and should not be used with them.
• Hormonal contraceptives – Symtuza may reduce the effectiveness of hormonal contraceptives. Alternative contraception may be required.

Pregnancy and Breastfeeding:

Information on the use of Symtuza during pregnancy is limited. Symtuza is not generally recommended during pregnancy, as drug levels may be reduced, potentially affecting viral control. People who become pregnant while taking Symtuza should consult their doctor promptly to review treatment options. Breastfeeding is not recommended for people living with HIV. HIV can be transmitted through breast milk, even when viral levels are low or undetectable. If you are pregnant, breastfeeding, or planning to become pregnant, it is crucial to consult your doctor immediately.

HBV Flare-up

Your doctor must test you for hepatitis B (HBV) before you start this medicine. If you have Hepatitis B, stopping Symtuza can cause a life-threatening liver flare-up. Always talk to your doctor before stopping.

Frequently Asked Questions about Symtuza at Canada Pharmacy Online:

Why is Symtuza more affordable in Canada than in the United States?

Prescription drug prices, including Symtuza, are generally lower in Canada than in the U.S. due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower prices than in the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to providing you with the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784. Visit our How to Order page for more information or to learn about the ordering process.

Is there a limit on the number of tablets I can order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Symtuza at a time, as per your doctor's prescription.

Can I buy over the counter from you?

No, Symtuza requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It typically takes 7-18 business days for your order to be delivered from our pharmacy.

Blog Post

Does Grapefruit Affect My Medications?

Latest News

WHO releases updated recommendations on HIV clinical management (published on January 6, 2026)

Similar Drugs in the category of AIDS Medications, HIV Treatments:

Atripla Combivir Biktarvy Epivir Reyataz

The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

Reviews From Real Customers